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Sildenafil Improved Pulmonary Hypertension and Peripheral Blood Flow in a Patient with Scleroderma-Associated Lung Fibrosis and the Raynaud Phenomenon
- Stephan Rosenkranz;
- Frank Diet;
- Thomas Karasch;
- Julia Weihrauch;
- Klaus Wassermann; and
- Erland Erdmann
- From Klinik III für Innere Medizin and Klinik und Poliklinik für Dermatologie; Universität zu Köln.
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TO THE EDITOR:
Background: Systemic scleroderma is a connective tissue disease involving several organ systems. Up to 90% of affected patients have the Raynaud phenomenon, and mortality rates largely depend on involvement of the lungs. In patients without pulmonary abnormalities, the 5-year survival rate is 90%, whereas in patients with systemic scleroderma–related pulmonary arterial …
