Cost-Effectiveness of Alternative Management Strategies for Patients with Solitary Pulmonary Nodules

Appendix (Figure 7). The ROC curve for CT is shown with 95% CIs ( ). Black diamonds represent individual study estimates of
sensitivity and specificity. The black circle represents the point on the summary ROC curve that corresponds to the median
specificity reported in 12 studies of noncontrast CT and high-resolution CT for pulmonary nodule diagnosis. At this point,
sensitivity and specificity were 96.5% and 55.8%, respectively. Note that the summary ROC curve for CT is not symmetrical.
Summary receiver-operating characteristic (ROC) curve for computed tomography (CT).dotted lines
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Ann Intern Med
May 6, 2003
vol. 138
no. 9
724-735