Cost-Effectiveness of Alternative Management Strategies for Patients with Solitary Pulmonary Nodules

Appendix (Figure 6). The ROC curves illustrate the tradeoff between sensitivity and specificity as the threshold that defines
a positive test result varies from most stringent to least stringent. The ROC curve for FDG-PET is shown with 95% CIs ( ).
Black diamonds represent individual study estimates of sensitivity and specificity. Four studies reported perfect sensitivity
and specificity ( ). The point on the summary ROC curve that corresponds to the median specificity reported in 13 studies
of FDG-PET for pulmonary nodule diagnosis is shown ( ). At this point, sensitivity and specificity were 94.2% and 83.3%, respectively.
Summary receiver-operating characteristic (ROC) curve for positron emission tomography with 18-fluorodeoxyglucose (FDG-PET).dotted
linesblack squareblack circle
-
Ann Intern Med
May 6, 2003
vol. 138
no. 9
724-735