Cost-Effectiveness of Alternative Management Strategies for Patients with Solitary Pulmonary Nodules

Appendix (Figure 5). The frequency plot demonstrates the distribution of observed doubling times for 67 pulmonary nodules
and mass lesions from the Veterans Administration–Armed Forces Cooperative Study on Asymptomatic Pulmonary Nodules . The monthly
probability of disease progression ( ) was assumed to be a function of the tumor doubling time.
Distribution of tumor doubling times and corresponding probabilities of disease progression during the observation period.(20)black
circles
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Ann Intern Med
May 6, 2003
vol. 138
no. 9
724-735