Cost-Effectiveness of Alternative Management Strategies for Patients with Solitary Pulmonary Nodules

Figure 2. The algorithm pertains to patients with low (10% to 50%), intermediate (51% to 76%), and high (77% to 90%) pretest
probability of malignancy. Note that in patients with very low pretest probability (<10%), biopsy is preferred when computed
tomography ( ) results are possibly malignant and watchful waiting is preferred when CT results suggest a benign diagnosis.
In patients with very high pretest probability (>90%), surgery without diagnostic testing is the preferred strategy. FDG-PET
= positron emission tomography with 18-fluorodeoxyglucose.
Suggested algorithm for clinical management of patients with solitary pulmonary nodules who are at average risk for surgical
complications.CT
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Ann Intern Med
May 6, 2003
vol. 138
no. 9
724-735