Cost-Effectiveness of Alternative Management Strategies for Patients with Solitary Pulmonary Nodules

Appendix (Figure 9). Test selection is shown to be a function of pretest probability and the corresponding post-test probability
once the results of CT are known. Recommendations are similar regardless of whether societal willingness to pay is $50 000
or $100 000 per quality-adjusted life-year ( ) gained. Note that surgery is preferred when positron emission tomography (
) results are positive, biopsy is preferred when PET results are negative, and watchful waiting is preferred when biopsy results
are nondiagnostic. FDG-PET = positron emission tomography with 18-fluorodeoxyglucose.
Recommended sequence of diagnostic testing in patients who are at average risk for surgical complications, according to pretest
probability, computed tomography (CT) results, and threshold that determines cost-effectiveness.QALYPET
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Ann Intern Med
May 6, 2003
vol. 138
no. 9
724-735