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Hepatitis B Virus Reactivation after a Single Session of Transarterial Chemoembolization in Patients with Hepatocellular Carcinoma
- Giovan B. Vizzini, MD;
- Angelo Luca, MD; and
- Ignazio R. Marino, MD
- Istituto Mediterraneo per i Trapianti e, Terapie ad Alta Specializzazione; 90134 Palermo, Italy (Vizzini, Luca, Marino) University of Pittsburgh Medical Center; Pittsburgh, PA 15213 (Vizzini, Luca, Marino)
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TO THE EDITOR:
Background: Hepatitis B virus (HBV) reactivation is a well-recognized complication in patients with cancer receiving systemic cytotoxic chemotherapy (1) and may cause varying degrees of liver damage. Immunosuppression due to cytotoxic therapy enhances viral replication and infection of the hepatocytes (2). Withdrawal of chemotherapy leads to restoration of immune function, with a consequent potential risk …
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