Long-Term Medical Care of Testicular Cancer Survivors
- David J. Vaughn, MD; and
- Anna T. Meadows, MD
- University of Pennsylvania Cancer Center; Philadelphia, PA 19104 (Vaughn) The Children's Hospital of Philadelphia; Philadelphia, PA 19104 (Meadows)
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IN RESPONSE:
Breast enlargement or tenderness may be an important, albeit uncommon, sign of the presence of an HCG-secreting germ-cell tumor. However, reversible gynecomastia may also develop in patients with germ-cell tumors several months after completion of cytotoxic chemotherapy. This is related not to disease recurrence but presumably to hormonal influences, since these patients may have elevated gonadotropin levels and an increased estradiol–testosterone ratio (1, 2). A normal serum HCG level in this setting should reassure both patient and physician.
David J. Vaughn, MD
University of Pennsylvania Cancer Center; Philadelphia, PA 19104
Anna T. Meadows, MD
The Children's Hospital of Philadelphia; Philadelphia, PA 19104
The Editors welcome submissions for possible publication in the Letters section. Authors of letters should:
•Include no more than 300 words of text, three authors, and five references
•Type with double-spacing
•Send three copies of the letter, an authors' form signed by all authors, and a cover letter describing any conflicts of interest related to the contents of the letter.
Letters commenting on an Annals article will be considered if they are received within 6 weeks of the time the article was published. Only some of the letters received can be published. Published letters are edited and may be shortened; tables and figures are included only selectively. Authors will be notified that the letter has been received. If the letter is selected for publication, the author will be notified about 3 weeks before the publication date. Unpublished letters cannot be returned.
Annals welcomes electronically submitted letters.
- Copyright ©2004 by the American College of Physicians
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