The Cost-Effectiveness of Cyclooxygenase-2 Selective Inhibitors in the Management of Chronic Arthritis

Figure 2. The summary estimate is the relative risk ( ). CLASS = Celecoxib Long-term Arthritis Safety Study; SUCCESS = Successive
Celecoxib Efficacy and Safety Study.
Meta-analysis using the fixed-effects model of randomized, controlled trials that report upper gastrointestinal dyspeptic
symptoms in patients receiving a coxib versus a nonselective nonsteroidal anti-inflammatory drug.RR
-
Ann Intern Med
May 20, 2003
vol. 138
no. 10
795-806