Table of Contents

October 15, 2002; 137 (8)

Articles

  • Outcome of Congestive Heart Failure in Elderly Persons: Influence of Left Ventricular Systolic Function: The Cardiovascular Health Study

    • John S. Gottdiener,
    • Robyn L. McClelland,
    • Robert Marshall,
    • Lynn Shemanski,
    • Curt D. Furberg,
    • Dalane W. Kitzman,
    • Mary Cushman,
    • Joseph Polak,
    • Julius M. Gardin,
    • Bernard J. Gersh,
    • Gerard P. Aurigemma,
    • and Teri A. Manolio
    Ann Intern Med October 15, 2002 137:631-639

    Community-dwelling elderly persons, especially those with impaired left ventricular function, have a substantial risk for death from congestive heart failure. However, more deaths occur from heart failure in persons with normal systolic function because left ventricular function is more often normal than impaired in elderly persons with heart failure.

  • Short-Course Rifampin and Pyrazinamide Compared with Isoniazid for Latent Tuberculosis Infection: A Multicenter Clinical Trial

    • Robert M. Jasmer,
    • Jussi J. Saukkonen,
    • Henry M. Blumberg,
    • Charles L. Daley,
    • John Bernardo,
    • Eric Vittinghoff,
    • Mark D. King,
    • L. Masae Kawamura,
    • Philip C. Hopewell,
    • and for the Short-Course Rifampin and Pyrazinamide for Tuberculosis Infection (SCRIPT) Study Investigators*
    Ann Intern Med October 15, 2002 137:640-647

    A 2-month regimen of rifampin and pyrazinamide for latent tuberculosis infection was associated with an increased risk for grade 3 or 4 hepatotoxicity compared with a 6-month regimen of isoniazid. Liver enzymes should be measured routinely during treatment to screen for liver injury and prevent progression to severe toxicity.

  • Ximelagatran versus Warfarin for the Prevention of Venous Thromboembolism after Total Knee Arthroplasty: A Randomized, Double-Blind Trial

    • Charles W. Francis,
    • Bruce L. Davidson,
    • Scott D. Berkowitz,
    • Paul A. Lotke,
    • Jeffrey S. Ginsberg,
    • Jay R. Lieberman,
    • Anne K. Webster,
    • James P. Whipple,
    • Gary R. Peters,
    • and Clifford W. Colwell Jr.
    Ann Intern Med October 15, 2002 137:648-655

    For prophylaxis of venous thromboembolism, fixed-dose ximelagatran started the morning after total knee arthroplasty is well tolerated and at least as effective as warfarin, but it does not require coagulation monitoring or dose adjustment.

Brief Communications

  • Relationship between Levels of Indinavir in Hair and Virologic Response to Highly Active Antiretroviral Therapy

    • Louis Bernard,
    • Albert Vuagnat,
    • Gilles Peytavin,
    • Marie-Charlotte Hallouin,
    • Damien Bouhour,
    • Thu Huyen Nguyen,
    • Jean Louis Vildé,
    • François Bricaire,
    • Gilles Raguin,
    • Pierre de Truchis,
    • David Ghez,
    • Michel Duong,
    • and Christian Perronne
    Ann Intern Med October 15, 2002 137:656-659

    Indinavir levels in hair are associated with virologic outcome in HIV-infected patients receiving highly active antiretroviral therapy.

Academia and Clinic

  • Ethical Considerations of Complementary and Alternative Medical Therapies in Conventional Medical Settings

    • Karen E. Adams,
    • Michael H. Cohen,
    • David Eisenberg,
    • and Albert R. Jonsen
    Ann Intern Med October 15, 2002 137:660-664

    Increasing use of complementary and alternative medical (CAM) therapies by patients, health care providers, and institutions has made it imperative that physicians consider their ethical obligations when recommending, tolerating, or proscribing these therapies. The authors present a risk–benefit framework that can be applied to determine the appropriateness of using CAM therapies in various clinical scenarios.

  • Hospital-Onset Infections: A Patient Safety Issue

    • Julie Louise Gerberding
    Ann Intern Med October 15, 2002 137:665-670

    Hospital-onset infections, particularly those involving the urinary tract, lung, and bloodstream, are common and costly and cause substantial morbidity. This article, part of the Quality Grand Rounds series, analyzes the case of a 78-year-old man with lung cancer who died after developing hospital-onset pneumonia and urinary catheter–related infection during hospitalization for elective removal of a cerebellar metastatic lesion.

Review

  • Breast Cancer in Men

    • Sharon H. Giordano,
    • Aman U. Buzdar,
    • and Gabriel N. Hortobagyi
    Ann Intern Med October 15, 2002 137:678-687

    Breast cancer is similar in men and women; however, breast cancer in men is more frequently hormone receptor positive and may be more sensitive to hormonal therapy.

Perspectives

  • New Federal Initiatives To Enhance the Medical Treatment of Opioid Dependence

    • David A. Fiellin and
    • Patrick G. O'Connor
    Ann Intern Med October 15, 2002 137:688-692

    Recent federal initiatives are designed to enhance the medical treatment of patients with opioid dependence and will expand the role of internists in the care of these patients. These initiatives include a process for federal exemptions to allow for pharmacologic treatment in office settings, waivers for the use of new medications, and new rules governing the oversight and distribution of opioid agonist medications for maintenance treatment.

Editorials

  • Rare Outcomes, Common Treatments: Analytic Strategies Using Propensity Scores

    • Leonard E. Braitman and
    • Paul R. Rosenbaum
    Ann Intern Med October 15, 2002 137:693-695

    Focusing on Jasmer and colleagues' study in this issue, the authors discuss the use of propensity scores to adjust for overt biases in treatment assignment in nonrandomized trials.

  • Hair It Is: The Long and Short of Monitoring Antiretroviral Treatment

    • Monica Gandhi and
    • Ruth M. Greenblatt
    Ann Intern Med October 15, 2002 137:696-697

    In this issue, Bernard and colleagues describe the relationship between the level of indinavir in hair, virologic response, and the occurrence of resistant HIV mutations. Their article provides evidence for a promising new option for monitoring exposure to antiretroviral regimens.

Letters

  • Chiropractic

    • Ronald L. Fredrickson
    Ann Intern Med October 15, 2002 137:W1

  • Quality Indicators for Prevention and Management of Pressure Ulcers

    • Thomas E. Finucane
    Ann Intern Med October 15, 2002 137:W2

  • Microbiologically Confirmed Early Lyme Disease

    • Edwin J. Masters
    Ann Intern Med October 15, 2002 137:698

  • Microbiologically Confirmed Early Lyme Disease

    • Robert P. Smith and
    • Allen C. Steere
    Ann Intern Med October 15, 2002 137:698

  • Resident Burnout

    • Ira S. Nash
    Ann Intern Med October 15, 2002 137:698-699

  • Resident Burnout

    • Joshua A. Beckman and
    • James C.-T. Fang
    Ann Intern Med October 15, 2002 137:699

  • Resident Burnout

    • W. Robert Graham
    Ann Intern Med October 15, 2002 137:699-700

  • Resident Burnout

    • Troy Madsen
    Ann Intern Med October 15, 2002 137:700

  • Resident Burnout

    • Anthony L. Back,
    • Joyce E. Wipf,
    • and Tait D. Shanafelt
    Ann Intern Med October 15, 2002 137:700

  • The Effect of HFE Genotypes on Measurements of Iron Overload

    • James A. Koziol,
    • Vincent J. Felitti,
    • and Ernest Beutler
    Ann Intern Med October 15, 2002 137:700-701

  • Chiropractic

    • Edzard Ernst
    Ann Intern Med October 15, 2002 137:701

  • Chiropractic

    • Daniel J. Fink
    Ann Intern Med October 15, 2002 137:701

  • Chiropractic

    • Ludmil A. Chotkowski
    Ann Intern Med October 15, 2002 137:702

  • Chiropractic

    • William C. Meeker and
    • Scott Haldeman
    Ann Intern Med October 15, 2002 137:702

  • East Asian Medicine

    • Linda L. Barnes
    Ann Intern Med October 15, 2002 137:702-703

  • East Asian Medicine

    • Ted J. Kaptchuk
    Ann Intern Med October 15, 2002 137:703

  • Intestinal Pseudo-Obstruction in a Diabetic Man: Role of the Mitochondrial A3243G Mutation

    • Yuji Aoki,
    • Shigetoshi Hosaka,
    • and Kendo Kiyosawa
    Ann Intern Med October 15, 2002 137:703-704

  • Immune Thrombocytopenia after Losartan Therapy

    • Sreenu Ada,
    • Madhuri Yalamanchili,
    • and William Friedenberg
    Ann Intern Med October 15, 2002 137:704

  • Favorable Long-Term Outcome of a Patient with Transcobalamin II Deficiency

    • Jean-Benoît Arlet,
    • Bruno Varet,
    • and Caroline Besson
    Ann Intern Med October 15, 2002 137:704-705

  • Correction: The Effect of HFE Genotypes on Measurements of Iron Overload

    Ann Intern Med October 15, 2002 137:705

Medical Writings: Book Notes

  • Primary Care Medicine Recommendations for PDA [CD-ROM]

    • Robert Badgett
    Ann Intern Med October 15, 2002 137:706

  • Clinical Management of Chronic Obstructive Pulmonary Disease

    • Warren Summer
    Ann Intern Med October 15, 2002 137:706

Book Listings

Medical Notices

Summaries for Patients

  • Heart Failure in the Elderly

    Ann Intern Med October 15, 2002 137:I-26

  • Short-Course Treatment for Latent Tuberculosis Is Associated with More Frequent Liver Injury Than Long-Course Treatment Is

    Ann Intern Med October 15, 2002 137:I-32

  • Ximelagatran versus Warfarin To Prevent Blood Clots after Knee Replacement Surgery

    Ann Intern Med October 15, 2002 137:I-38

  • The Relationship between Levels of the Anti-HIV Drug Indinavir in Patients' Hair and Response to Treatment

    Ann Intern Med October 15, 2002 137:I-48

  • Breast Cancer in Men

    Ann Intern Med October 15, 2002 137:I-63

Updates from the Annual Session

  • Update in Psychiatry

    • Robert K. Schneider and
    • James L. Levenson
    Ann Intern Med October 15, 2002 137:671-677

    This Update covers mood disorders, anxiety disorders, medical–psychiatric comorbid conditions, and cognitive disorders.

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This Issue

October 15, 2002; 137 (8)
  1. Articles
  2. Brief Communications
  3. Academia and Clinic
  4. Review
  5. Perspectives
  6. Editorials
  7. Letters
  8. Medical Writings: Book Notes
  9. Book Listings
  10. Medical Notices
  11. Summaries for Patients
  12. Updates from the Annual Session

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