Table of Contents

December 17, 2002; 137 (12)

Articles

  • Treatment of the Common Cold with Unrefined Echinacea: A Randomized, Double-Blind, Placebo-Controlled Trial

    • Bruce P. Barrett,
    • Roger L. Brown,
    • Kristin Locken,
    • Rob Maberry,
    • James A. Bobula,
    • and Donn D'Alessio
    Ann Intern Med December 17, 2002 137:939-946

    Compared with placebo, unrefined echinacea provided no detectable benefit or harm in college students who had the common cold.

  • Results of a Prospective Study of Acute Liver Failure at 17 Tertiary Care Centers in the United States

    • George Ostapowicz,
    • Robert J. Fontana,
    • Frank V. Schiødt,
    • Anne Larson,
    • Timothy J. Davern,
    • Steven H.B. Han,
    • Timothy M. McCashland,
    • A. Obaid Shakil,
    • J. Eileen Hay,
    • Linda Hynan,
    • Jeffrey S. Crippin,
    • Andres T. Blei,
    • Grace Samuel,
    • Joan Reisch,
    • William M. Lee,
    • and the U.S. Acute Liver Failure Study Group*
    Ann Intern Med December 17, 2002 137:947-954

    Acetaminophen overdose and idiosyncratic drug reactions have replaced viral hepatitis as the most frequent causes of acute liver failure. The cause of liver failure and coma grade at admission were associated with outcome. Although transplantation may improve patient survival, most patients did not need it or could not get it.

  • Residual Venous Thrombosis as a Predictive Factor of Recurrent Venous Thromboembolism

    • Paolo Prandoni,
    • Anthonie W.A. Lensing,
    • Martin H. Prins,
    • Enrico Bernardi,
    • Antonio Marchiori,
    • Paola Bagatella,
    • Michela Frulla,
    • Laura Mosena,
    • Daniela Tormene,
    • Andrea Piccioli,
    • Paolo Simioni,
    • and Antonio Girolami
    Ann Intern Med December 17, 2002 137:955-960

    Residual venous thrombosis after discontinuing anticoagulation is an important risk factor for recurrent thromboembolism. Assessing residual venous thrombosis with ultrasonography may help clinicians to identify patients who need prolonged anticoagulation.

Brief Communications

  • Prevalence of Liver Disease in a Population of Asymptomatic Persons with Hepatitis C Virus Infection

    • Alfredo Alberti,
    • Franco Noventa,
    • Luisa Benvegnù,
    • Silvia Boccato,
    • and Angelo Gatta
    Ann Intern Med December 17, 2002 137:961-964

    Up to 40% of asymptomatic persons with hepatitis C virus infection have histologically active and progressive hepatitis. The severity of liver disease correlates with abnormal alanine aminotransferase levels and increases with age.

Academia and Clinic

  • Credentialing Complementary and Alternative Medical Providers

    • David M. Eisenberg,
    • Michael H. Cohen,
    • Andrea Hrbek,
    • Jonathan Grayzel,
    • Maria I. Van Rompay,
    • and Richard A. Cooper
    Ann Intern Med December 17, 2002 137:965-973

    This article describes models for health care credentialing of chiropractors, acupuncturists, naturopaths, massage therapists, and other complementary and alternative medical (CAM) practitioners. It also suggests a strategy of CAM provider credentialing for use by physicians, health care administrators, insurance companies, and national professional organizations.

Review

  • Novel Insights in the Congenital Long QT Syndrome

    • Xander H.T. Wehrens,
    • Marc A. Vos,
    • Pieter A. Doevendans,
    • and Hein J.J. Wellens
    Ann Intern Med December 17, 2002 137:981-992

    The congenital long QT syndrome is a potentially life-threatening condition caused by mutations in genes encoding cardiac ion channels. The increasing understanding of the mechanisms responsible for these conditions should lead to genotype-specific therapy.

History of Medicine

  • Smallpox Manifestations and Survival during the Boston Epidemic of 1901 to 1903

    • Michael R. Albert,
    • Kristen G. Ostheimer,
    • David J. Liewehr,
    • Seth M. Steinberg,
    • and Joel G. Breman
    Ann Intern Med December 17, 2002 137:993-1000

    The authors describe clinical manifestations of smallpox during Boston's last major epidemic (1901–1903) and analyze factors associated with survival among patients admitted to one hospital.

Editorial

  • Echinacea for the Common Cold: Can Alternative Medicine Be Evidence-Based Medicine?

    • Ronald B. Turner
    Ann Intern Med December 17, 2002 137:1001-1002

    The study by Barrett and colleagues in this issue is a valuable contribution to the literature on echinacea because it addresses many shortcomings of earlier studies. Although the study was carefully done and the results are clear, their work is not likely to end the discussion about the efficacy of echinacea for the common cold.

On Being a Doctor

  • The Healing Touch

    • Lucie Opatrny
    Ann Intern Med December 17, 2002 137:1003

    He reached out to grasp my resting hand. Then, suddenly, this man, who had until now spoken and moved so very slowly, started rapidly and vigorously rubbing my hand between both of his. “To warm you up, doctor. My wife also gets cold when she's tired. This has always helped her,” Mr. B. explained, never taking his eyes off his task. “You should be sleeping to take care of yourself instead of old men like me,” he added.

On Being a Patient

  • Trust

    • Samuel C. Durso
    Ann Intern Med December 17, 2002 137:1004-1005

    I was struck by the irony of this doctor–patient relationship. In the office our relationship was conventional. He was the heart patient and I was his doctor. The marsh was different. Here Ezra and I were in each other's hands.

Letters

  • Careful Conversation about Care at the End of Life

    • Tatsuya Morita,
    • Satoru Tsuneto,
    • and Yasuo Shima
    Ann Intern Med December 17, 2002 137:W1

  • Careful Conversation about Care at the End of Life

    • John H. Kvasnicka
    Ann Intern Med December 17, 2002 137:W2

  • Reporting Enrollment in Clinical Trials

    • Scott D. Halpern
    Ann Intern Med December 17, 2002 137:1007

  • Reporting Enrollment in Clinical Trials

    • Joseph H. Friedman
    Ann Intern Med December 17, 2002 137:1007

  • Reporting Enrollment in Clinical Trials

    • Gregory A. Abel
    Ann Intern Med December 17, 2002 137:1007

  • Reporting Enrollment in Clinical Trials

    • Cary P. Gross and
    • Harlan Krumholz
    Ann Intern Med December 17, 2002 137:1008

  • The Risk–Benefit Profile of Commonly Used Herbal Therapies

    • Sanford H. Levy
    Ann Intern Med December 17, 2002 137:1008

  • The Risk–Benefit Profile of Commonly Used Herbal Therapies

    • Edzard Ernst
    Ann Intern Med December 17, 2002 137:1008

  • Careful Conversation about Care at the End of Life

    • Charles G. Sasser
    Ann Intern Med December 17, 2002 137:1008-1009

  • Careful Conversation about Care at the End of Life

    • Timothy E. Quill
    Ann Intern Med December 17, 2002 137:1009

  • Careful Conversation about Care at the End of Life

    • Paul Rousseau
    Ann Intern Med December 17, 2002 137:1009-1010

  • Careful Conversation about Care at the End of Life

    • Lynn A. Jansen and
    • Daniel P. Sulmasy
    Ann Intern Med December 17, 2002 137:1010

  • Physician Involvement in Voluntary Stopping of Eating and Drinking

    • Bernard Gert,
    • James L. Bernat,
    • and R. Peter Mogielnicki
    Ann Intern Med December 17, 2002 137:1010-1011

  • Physician Involvement in Voluntary Stopping of Eating and Drinking

    • Lynn A. Jansen and
    • Daniel P. Sulmasy
    Ann Intern Med December 17, 2002 137:1011

  • Reflections on Medical Journals

    • David Moher,
    • Kenneth F. Schulz,
    • Douglas G. Altman,
    • and Drummond Rennie
    Ann Intern Med December 17, 2002 137:1011-1012

  • Reflections on Medical Journals

    • Jerome P. Kassirer
    Ann Intern Med December 17, 2002 137:1012

  • Use of Antiviral Therapy in Patients with Hepatitis C

    • Catherine Diamond and
    • Jea Hyun Lee
    Ann Intern Med December 17, 2002 137:1012

  • Angina Caused by Calcific Constrictive Pericarditis

    • Isabelle Mahé,
    • Eric Braunberger,
    • and Jean-François Bergmann
    Ann Intern Med December 17, 2002 137:1012-1013

  • Foamy Macrophage Syndrome due to Hydroxyethyl Starch Replacement: A Severe Side Effect in Plasmapheresis

    • Johannes J.A. Auwerda,
    • J.H. Paul Wilson,
    • and Pieter Sonneveld
    Ann Intern Med December 17, 2002 137:1013-1014

  • Recertification

    • Robert S. Crausman
    Ann Intern Med December 17, 2002 137:1014

Ad Libitum

Thanks to Reviewers

Book Listings

Medical Notices

Summaries for Patients

  • Treatment of Colds with a Capsule Form of the Herb Echinacea

    Ann Intern Med December 17, 2002 137:I-18

  • Acute Liver Failure in the United States

    Ann Intern Med December 17, 2002 137:I-24

  • Risks for Persistent Clots in Leg Veins despite Treatment

    Ann Intern Med December 17, 2002 137:I-32

  • Liver Disease in Persons with Asymptomatic Hepatitis C Virus Infection

    Ann Intern Med December 17, 2002 137:I-36

  • When the Heart's Electrical System Goes Haywire: The Congenital Long QT Syndrome

    Ann Intern Med December 17, 2002 137:I-43

Updates from the Annual Session

  • Update in Infectious Diseases

    • Bennett Lorber
    Ann Intern Med December 17, 2002 137:974-980

    This Update covers terrorist threats to the health of the public, new approaches to some familiar clinical problems, newly recognized disorders, novel treatments for infectious diseases, HIV infection, and infectious complications of treatment for other illnesses.

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This Issue

December 17, 2002; 137 (12)
  1. Articles
  2. Brief Communications
  3. Academia and Clinic
  4. Review
  5. History of Medicine
  6. Editorial
  7. On Being a Doctor
  8. On Being a Patient
  9. Letters
  10. Ad Libitum
  11. Thanks to Reviewers
  12. Book Listings
  13. Medical Notices
  14. Summaries for Patients
  15. Updates from the Annual Session

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