Chemoprevention of Breast Cancer: A Summary of the Evidence for the U.S. Preventive Services Task Force
- Linda S. Kinsinger, MD, MPH;
- Russell Harris, MD, MPH;
- Steven H. Woolf, MD, MPH;
- Harold C. Sox, MD; and
- Kathleen N. Lohr, PhD
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From Cecil G. Sheps Center for Health Services Research, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina;
Virginia Commonwealth University, Fairfax, Virginia; American College of Physicians-American Society of Internal Medicine,
Philadelphia, Pennsylvania; and Research Triangle Institute, Research Triangle Park, North Carolina.
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Figure. Harms include endometrial cancer, stroke, and pulmonary embolism combined. Adapted from reference . Benefits and harms of chemoprevention with tamoxifen per 10 000 women in three age groups.49
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Appendix (Figure 1). KQ = key question. KQ 1: Do chemopreventive agents reduce mortality from breast cancer? KQ 2: Do chemopreventive
agents reduce the incidence of breast cancer? KQ 3: Do chemopreventive agents have other beneficial effects? KQ 4: Do chemopreventive
agents increase the risk for adverse effects? KQ 5: What are the costs associated with chemoprevention of breast cancer? Analytical framework.
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Appendix (Figure 2). RCTs = randomized, controlled trials. Article selection.
- Copyright ©2004 by the American College of Physicians
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Ann Intern Med
July 2, 2002
vol. 137
no. 1
59-69
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Figure. Harms include endometrial cancer, stroke, and pulmonary embolism combined. Adapted from reference . Benefits and harms of chemoprevention with tamoxifen per 10 000 women in three age groups.49
Appendix (Figure 1). KQ = key question. KQ 1: Do chemopreventive agents reduce mortality from breast cancer? KQ 2: Do chemopreventive agents reduce the incidence of breast cancer? KQ 3: Do chemopreventive agents have other beneficial effects? KQ 4: Do chemopreventive agents increase the risk for adverse effects? KQ 5: What are the costs associated with chemoprevention of breast cancer? Analytical framework.
Appendix (Figure 2). RCTs = randomized, controlled trials. Article selection.
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