Acquired Aplastic Anemia

Figure 1. These syndromes include clonal diseases (paroxysmal nocturnal hemoglobinuria, myelodysplasia, and large granular lymphocytosis); and single hematopoietic lineage deficiency diseases (agranuloyctosis, pure red-cell aplasia, and amegakaryocytic thrombocytopenia); note especially the areas of overlap between aplastic anemia and paroxysmal nocturnal hemoglobinuria and myelodysplasia.
Figure 1. These syndromes include clonal diseases (paroxysmal nocturnal hemoglobinuria, myelodysplasia, and large granular lymphocytosis); and single hematopoietic lineage deficiency diseases (agranuloyctosis, pure red-cell aplasia, and amegakaryocytic thrombocytopenia); note especially the areas of overlap between aplastic anemia and paroxysmal nocturnal hemoglobinuria and myelodysplasia. Venn diagram showing possible relationships among bone marrow failure syndromes.

This Article

  1. Ann Intern Med April 2, 2002 vol. 136 no. 7 534-546