Table of Contents

December 4, 2001; 135 (11)

Articles

  • Estrogen in the Prevention of Atherosclerosis: A Randomized, Double-Blind, Placebo-Controlled Trial

    • Howard N. Hodis,
    • Wendy J. Mack,
    • Roger A. Lobo,
    • Donna Shoupe,
    • Alex Sevanian,
    • Peter R. Mahrer,
    • Robert H. Selzer,
    • Chao-ran Liu,
    • Ci-hua Liu,
    • Stanley P. Azen,
    • and for the Estrogen in the Prevention of Atherosclerosis Trial Research Group*
    Ann Intern Med December 4, 2001 135:939-953

    Overall, the average rate of progression of subclinical atherosclerosis was slower in healthy postmenopausal women taking unopposed estrogen replacement therapy with 17β-estradiol than in women taking placebo. Progression of subclinical atherosclerosis decreased in women who did not take lipid-lowering medication but not in those who took these medications.

  • Predictors of Virologic and Clinical Outcomes in HIV-1–Infected Patients Receiving Concurrent Treatment with Indinavir, Zidovudine, and Lamivudine: AIDS Clinical Trials Group Protocol 320

    • Lisa M. Demeter,
    • Michael D. Hughes,
    • Robert W. Coombs,
    • J. Brooks Jackson,
    • Janet M. Grimes,
    • Ronald J. Bosch,
    • Susan A. Fiscus,
    • Stephen A. Spector,
    • Kathleen E. Squires,
    • Margaret A. Fischl,
    • and Scott M. Hammer
    Ann Intern Med December 4, 2001 135:954-964

    The HIV-1 RNA level and CD4 cell count achieved at 8 weeks of indinavir, zidovudine, and lamivudine therapy are important predictors of subsequent virologic and clinical outcomes.

  • Resistance Training To Counteract the Catabolism of a Low-Protein Diet in Patients with Chronic Renal Insufficiency: A Randomized, Controlled Trial

    • Carmen Castaneda,
    • Patricia L. Gordon,
    • Katherine Leigh Uhlin,
    • Andrew S. Levey,
    • Joseph J. Kehayias,
    • Johanna T. Dwyer,
    • Roger A. Fielding,
    • Ronenn Roubenoff,
    • and Maria Fiatarone Singh
    Ann Intern Med December 4, 2001 135:965-976

    By improving muscle mass, nutritional status, and function, resistance training seems to be effective against the catabolism of a low-protein diet and uremia in patients with renal failure.

Brief Communications

  • Menstrual Cyclic Variation of Myocardial Ischemia in Premenopausal Women with Variant Angina

    • Hiroaki Kawano,
    • Takeshi Motoyama,
    • Masamichi Ohgushi,
    • Kiyotaka Kugiyama,
    • Hisao Ogawa,
    • and Hirofumi Yasue
    Ann Intern Med December 4, 2001 135:977-981

    In premenopausal women with variant angina, the authors documented a cyclic variation in endothelial function and the frequency of myocardial ischemia that was associated with the variation in estrogen levels.

Academia and Clinic

  • Reported Methodologic Quality and Discrepancies between Large and Small Randomized Trials in Meta-Analyses

    • Lise L. Kjaergard,
    • John Villumsen,
    • and Christian Gluud
    Ann Intern Med December 4, 2001 135:982-989

    Inadequate generation of the allocation sequence, allocation concealment, and double blinding lead to exaggerated estimates of intervention benefit and may contribute to discrepancies between the results of large randomized trials and small randomized trials in meta-analyses.

Review

  • Automated External Defibrillators: Technical Considerations and Clinical Promise

    • Theodore S. Takata,
    • Richard L. Page,
    • and Jose A. Joglar
    Ann Intern Med December 4, 2001 135:990-998

    The authors provide general information on the technology and operation of automated external defibrillators, summarize the experience of trials of these devices (in emergency medical systems and in special environments), and discuss legislative and legal concerns.

Editorials

  • Resistance Training Enhances the Value of Protein Restriction in the Treatment of Chronic Kidney Disease

    • John B. Copley
    Ann Intern Med December 4, 2001 135:999-1001

    Castaneda and colleagues' results, reported in this issue, suggest that resistance training is a safe and effective countermeasure to the negative effects of protein restriction on muscle mass accretion, protein utilization, nutritional status, and muscle function in patients with chronic kidney disease. Their study provides a method for improving safety when protein-restricted diets are used, as well as a means for enhancing the overall health of patients with chronic kidney disease.

  • Coronary Artery Disease in Young Women: The Menstrual Cycle and Other Risk Factors

    • Pamela Charney
    Ann Intern Med December 4, 2001 135:1002-1004

    In this issue, Kawano and colleagues elegantly explore the relationship of endogenous hormone levels to arterial function and coronary ischemic symptoms. Consideration of the interaction of the menstrual cycle and coronary artery disease may affect clinical practice in the not-distant future.

Letters

  • Clinical Trial Acronyms

    • Paul I. Roda
    Ann Intern Med December 4, 2001 135:1005

  • Clinical Trial Acronyms

    • Tsung O. Cheng
    Ann Intern Med December 4, 2001 135:1005

  • Clinical Trial Acronyms

    • Michael Berkwits
    Ann Intern Med December 4, 2001 135:1005-1006

  • Methotrexate in Giant-Cell Arteritis

    • Sarah L. Morgan and
    • Graciela S. Alarcón
    Ann Intern Med December 4, 2001 135:1006

  • Methotrexate in Giant-Cell Arteritis

    • Robert F. Spiera,
    • Stephen Paget,
    • and Harry Spiera
    Ann Intern Med December 4, 2001 135:1006-1007

  • Methotrexate in Giant-Cell Arteritis

    • Juan A. Jover,
    • César Hernández-García,
    • and Benjamín Fernández-Gutiérrez
    Ann Intern Med December 4, 2001 135:1007

  • Nonhypoglycemic Effects of Thiazolidinediones

    • Jose Manuel Quesada-Gómez and
    • Ignacio Serrano-Alferez
    Ann Intern Med December 4, 2001 135:1007-1008

  • New Psychopharmacologic Treatment Strategies

    • Peter E. Stokes
    Ann Intern Med December 4, 2001 135:1008

  • New Psychopharmacologic Treatment Strategies

    • Ira D. Glick and
    • Charles DeBattista
    Ann Intern Med December 4, 2001 135:1008

  • Albumin Meta-Analysis

    • Eric M. Gibney
    Ann Intern Med December 4, 2001 135:1008-1009

  • Albumin Meta-Analysis

    • Mahlon M. Wilkes and
    • Roberta J. Navickis
    Ann Intern Med December 4, 2001 135:1009

  • Clinical Librarianship

    • Charles R. Fikar
    Ann Intern Med December 4, 2001 135:1009-1010

  • Sympathetic Neurocirculatory Failure in Parkinson Disease: Evidence for an Etiologic Role of α-Synuclein

    • David S. Goldstein,
    • Sheng-Ting Li,
    • and Irwin J. Kopin
    Ann Intern Med December 4, 2001 135:1010-1011

  • Severe Neurotoxicity of Cefepime in Uremic Patients

    • Frédéric Barbey,
    • Denis Bugnon,
    • and Jean-Pierre Wauters
    Ann Intern Med December 4, 2001 135:1011

Medical Writings

  • The Physician as Storyteller

    • Abraham Verghese
    Ann Intern Med December 4, 2001 135:1012-1017

    By being attuned to character, not just through appearance but particularly through dialogue, we will remember the voice of the patient, even though it is the voice of medicine that we record in the chart. To hear the voice of the patient preserves our capacity to imagine the suffering of the patient.

Medical Writings: Book Notes

Ad Libitum

Book Listings

Medical Notices

Summaries for Patients

  • Postmenopausal Estrogen Helps Prevent Atherosclerosis in Some Women

    Ann Intern Med December 4, 2001 135:S58

  • Predictors of Outcomes in Patients with HIV Infection Treated with Indinavir, Zidovudine, and Lamivudine

    Ann Intern Med December 4, 2001 135:S59

  • Weight-Training Exercises To Counteract the Negative Effects of Low-Protein Diets in People with Kidney Disease

    Ann Intern Med December 4, 2001 135:S60

  • Blood Flow to the Heart Varies during the Menstrual Cycle in Premenopausal Women with Heart Disease

    Ann Intern Med December 4, 2001 135:S61
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This Issue

December 4, 2001; 135 (11)
  1. Articles
  2. Brief Communications
  3. Academia and Clinic
  4. Review
  5. Editorials
  6. Letters
  7. Medical Writings
  8. Medical Writings: Book Notes
  9. Ad Libitum
  10. Book Listings
  11. Medical Notices
  12. Summaries for Patients

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