Osteoarthritis: New Insights. Part 1: The Disease and Its Risk Factors

  1. Conference Chair: David T. Felson, MD, MPH;
  2. Conference Organizer: Reva C. Lawrence, MPH;
  3. Discussants: Paul A. Dieppe, MD;
  4. Rosemarie Hirsch, MD, MPH;
  5. Charles G. Helmick, MD;
  6. Joanne M. Jordan, MD, MPH;
  7. Raynard S. Kington, MD, PhD;
  8. Nancy E. Lane, MD;
  9. Michael C. Nevitt, PhD;
  10. Yuqing Zhang, DSc;
  11. MaryFran Sowers, PhD;
  12. Timothy McAlindon, MD, MPH;
  13. Tim D. Spector, MD, MSc;
  14. A. Robin Poole, PhD, DSc;
  15. Susan Z. Yanovski, MD;
  16. Gerard Ateshian, PhD;
  17. Leena Sharma, MD;
  18. Joseph A. Buckwalter, MD;
  19. Kenneth D. Brandt, MD; and
  20. James F. Fries, MD
  1. From Boston University School of Medicine, Boston, Massachusetts; National Institute of Arthritis and Musculoskeletal and Skin Diseases and National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland; MRC Health Services Research Collaboration, University of Bristol, Bristol, United Kingdom; Centers for Disease Control and Prevention, Atlanta, Georgia; University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; University of California, San Francisco, San Francisco, and Stanford University School of Medicine, Palo Alto, California; University of Michigan, Ann Arbor, Michigan; St. Thomas' Hospital, London, United Kingdom; Shriners Hospital for Children and McGill University, Montreal, Quebec, Canada; Columbia University, New York, New York; Northwestern University, Chicago, Illinois; University of Iowa Hospitals, Iowa City, Iowa; and Indiana University School of Medicine, Indianapolis, Indiana.
    1. Figure 1. Reproduced with permission from reference .
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        Figure 1. Reproduced with permission from reference . Incidence of osteoarthritis of the hand, hip, and knee in members of the Fallon Community Health Plan, 1991–1992, by age and sex.9
      • Figure 2. Modified with permission from of Dieppe P. The classification and diagnosis of osteoarthritis. In: Kuettner K, Goldberg V, eds. Osteoarthritic Disorders. Rosemont, IL: American Academy of Orthopaedic Surgeons; 1995:7.
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          Figure 2. Modified with permission from of Dieppe P. The classification and diagnosis of osteoarthritis. In: Kuettner K, Goldberg V, eds. Osteoarthritic Disorders. Rosemont, IL: American Academy of Orthopaedic Surgeons; 1995:7. Pathogenesis of osteoarthritis with putative risk factors.Figure 1
        • Figure 3. Reproduced with permission from reference .
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            Figure 3. Reproduced with permission from reference . Direction of force application and the resulting motion at the knee in the determination of varus–valgus laxity in the right lower extremity.60
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