Osteoarthritis: New Insights. Part 1: The Disease and Its Risk Factors

  1. Conference Chair: David T. Felson, MD, MPH;
  2. Conference Organizer: Reva C. Lawrence, MPH;
  3. Discussants: Paul A. Dieppe, MD;
  4. Rosemarie Hirsch, MD, MPH;
  5. Charles G. Helmick, MD;
  6. Joanne M. Jordan, MD, MPH;
  7. Raynard S. Kington, MD, PhD;
  8. Nancy E. Lane, MD;
  9. Michael C. Nevitt, PhD;
  10. Yuqing Zhang, DSc;
  11. MaryFran Sowers, PhD;
  12. Timothy McAlindon, MD, MPH;
  13. Tim D. Spector, MD, MSc;
  14. A. Robin Poole, PhD, DSc;
  15. Susan Z. Yanovski, MD;
  16. Gerard Ateshian, PhD;
  17. Leena Sharma, MD;
  18. Joseph A. Buckwalter, MD;
  19. Kenneth D. Brandt, MD; and
  20. James F. Fries, MD
  1. From Boston University School of Medicine, Boston, Massachusetts; National Institute of Arthritis and Musculoskeletal and Skin Diseases and National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland; MRC Health Services Research Collaboration, University of Bristol, Bristol, United Kingdom; Centers for Disease Control and Prevention, Atlanta, Georgia; University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; University of California, San Francisco, San Francisco, and Stanford University School of Medicine, Palo Alto, California; University of Michigan, Ann Arbor, Michigan; St. Thomas' Hospital, London, United Kingdom; Shriners Hospital for Children and McGill University, Montreal, Quebec, Canada; Columbia University, New York, New York; Northwestern University, Chicago, Illinois; University of Iowa Hospitals, Iowa City, Iowa; and Indiana University School of Medicine, Indianapolis, Indiana.
    1. Figure 1. Reproduced with permission from reference .
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      Figure 1. Reproduced with permission from reference . Incidence of osteoarthritis of the hand, hip, and knee in members of the Fallon Community Health Plan, 1991–1992, by age and sex.9
    2. Figure 2. Modified with permission from of Dieppe P. The classification and diagnosis of osteoarthritis. In: Kuettner K, Goldberg V, eds. Osteoarthritic Disorders. Rosemont, IL: American Academy of Orthopaedic Surgeons; 1995:7.
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      Figure 2. Modified with permission from of Dieppe P. The classification and diagnosis of osteoarthritis. In: Kuettner K, Goldberg V, eds. Osteoarthritic Disorders. Rosemont, IL: American Academy of Orthopaedic Surgeons; 1995:7. Pathogenesis of osteoarthritis with putative risk factors.Figure 1
    3. Figure 3. Reproduced with permission from reference .
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      Figure 3. Reproduced with permission from reference . Direction of force application and the resulting motion at the knee in the determination of varus–valgus laxity in the right lower extremity.60
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