A Systematic Review of Newer Pharmacotherapies for Depression in Adults: Evidence Report Summary: Clinical Guideline, Part
2
- John W. Williams, Jr., MD, MHS;
- Cynthia D. Mulrow, MD, MSc;
- Elaine Chiquette, PharmD;
- Polly Hitchcock Noël, PhD;
- Christine Aguilar, MD, MPH; and
- John Cornell, PhD
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From the South Texas Veterans Health Care System, Audie Murphy Division and the San Antonio Evidence-based Practice Center,
University of Texas Health Science Center at San Antonio, San Antonio, Texas.
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Figure 1. indicates number of participants; indicates number of studies. GABA = γ-aminobutyric acid; HT = hydroxy-tryptophan;
RIMA = reversible inhibitor of monoamine oxidase A; SSRI = selective serotonin reuptake inhibitor; SNRI = serotonin and noradrenaline
reuptake inhibitor. Meta-analysis of placebo compared with newer antidepressants for major depression in adults.Nn
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Figure 2. . indicates number of participants; indicates number of studies. HT = hydroxy-tryptophan; MAOI = monoamine oxidase
inhibitor; NRI = norepinephrine reuptake inhibitor; RIMA = reversible inhibitor of monoamine oxidase A; SSRI = selective serotonin
reuptake inhibitor; SNRI = serotonin and noradrenaline reuptake inhibitor; TCA1 = first-generation tricyclic antidepressant;
TCA2 = second-generation tricyclic antidepressant. Meta-analysis of older antidepressants compared with newer antidepressants for major depression in adultsNn
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Figure 3. indicates number of participants. *Response rates not given. HT = hydroxy-tryptophan; SSRI = selective serotonin
reuptake inhibitor. Meta-analysis of newer antidepressants for dysthymia in adults.N
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Figure 4. indicates number of participants. The diamonds represent a summary estimate, derived from the individual studies
listed above the diamonds. The center of each diamond is the point estimate, and the tails represent the 95% CIs. Meta-analysis of hypericum (St. John's wort) for depressive disorders in adults.N
- Copyright ©2004 by the American College of Physicians
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Ann Intern Med
May 2, 2000
vol. 132
no. 9
743-756
RSS Feeds
Figure 1. indicates number of participants; indicates number of studies. GABA = γ-aminobutyric acid; HT = hydroxy-tryptophan; RIMA = reversible inhibitor of monoamine oxidase A; SSRI = selective serotonin reuptake inhibitor; SNRI = serotonin and noradrenaline reuptake inhibitor. Meta-analysis of placebo compared with newer antidepressants for major depression in adults.Nn
Figure 2. . indicates number of participants; indicates number of studies. HT = hydroxy-tryptophan; MAOI = monoamine oxidase inhibitor; NRI = norepinephrine reuptake inhibitor; RIMA = reversible inhibitor of monoamine oxidase A; SSRI = selective serotonin reuptake inhibitor; SNRI = serotonin and noradrenaline reuptake inhibitor; TCA1 = first-generation tricyclic antidepressant; TCA2 = second-generation tricyclic antidepressant. Meta-analysis of older antidepressants compared with newer antidepressants for major depression in adultsNn
Figure 3. indicates number of participants. *Response rates not given. HT = hydroxy-tryptophan; SSRI = selective serotonin reuptake inhibitor. Meta-analysis of newer antidepressants for dysthymia in adults.N
Figure 4. indicates number of participants. The diamonds represent a summary estimate, derived from the individual studies listed above the diamonds. The center of each diamond is the point estimate, and the tails represent the 95% CIs. Meta-analysis of hypericum (St. John's wort) for depressive disorders in adults.N
