The Effect of Coenzyme Q10 in Patients with Congestive Heart Failure

  1. Meenakshi Khatta, MS, CRNP;
  2. Barbara S. Alexander, MD, PhD;
  3. Cathy M. Krichten, MS, CRNP;
  4. Michael L. Fisher, MD;
  5. Ronald Freudenberger, MD;
  6. Shawn W. Robinson, MD; and
  7. Stephen S. Gottlieb, MD
  1. From University of Maryland School of Medicine and Veterans Affairs Medical Center, Baltimore, Maryland.
    1. Figure 1. Coenzyme Q had no overall effect. The mean ± SD is shown for each time point.
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      Figure 1. Coenzyme Q had no overall effect. The mean ± SD is shown for each time point. Ejection fraction and peak oxygen consumption before and after the treatment period for each patient who received placebo (left) and coenzyme Q 10 (right).10
    2. Figure 2. Circles represent patients who received active treatment, and crosses represent patients who received placebo. The study drug clearly increased serum concentrations of coenzyme Q . However, there was no relation between the change in serum concentration and the change in peak oxygen consumption.
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      Figure 2. Circles represent patients who received active treatment, and crosses represent patients who received placebo. The study drug clearly increased serum concentrations of coenzyme Q . However, there was no relation between the change in serum concentration and the change in peak oxygen consumption. The change in coenzyme Q 10 concentration compared with the change in peak oxygen consumption.10
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    This Article

    1. Ann Intern Med April 18, 2000 vol. 132 no. 8 636-640
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