Table of Contents

April 18, 2000; 132 (8)

Articles

  • Low Cardiorespiratory Fitness and Physical Inactivity as Predictors of Mortality in Men with Type 2 Diabetes

    • Ming Wei,
    • Larry W. Gibbons,
    • James B. Kampert,
    • Milton Z. Nichaman,
    • and Steven N. Blair
    Ann Intern Med April 18, 2000 132:605-611

    Low cardiorespiratory fitness and physical inactivity were found to be independent predictors of all-cause mortality in men with type 2 diabetes. Physicians should encourage patients with this disease to participate in regular physical activity and improve their cardiorespiratory fitness.

  • Effect of Segment Length on Risk for Neoplastic Progression in Patients with Barrett Esophagus

    • Rebecca E. Rudolph,
    • Thomas L. Vaughan,
    • Barry E. Storer,
    • Rodger C. Haggitt,
    • Peter S. Rabinovitch,
    • Douglas S. Levine,
    • and Brian J. Reid
    Ann Intern Med April 18, 2000 132:612-620

    The risk for esophageal adenocarcinoma in patients with short-segment Barrett esophagus was not substantially lower than that in patients with longer segments. Although the findings of this study suggest a small increase in risk for neoplastic progression with increasing segment length, additional follow-up is needed to determine whether the patterns of risk occurred by chance or represent true differences.

  • Invasive and Noninvasive Strategies for Management of Suspected Ventilator-Associated Pneumonia: A Randomized Trial

    • Jean-Yves Fagon,
    • Jean Chastre,
    • Michel Wolff,
    • Claude Gervais,
    • Sylvie Parer-Aubas,
    • François Stéphan,
    • Thomas Similowski,
    • Alain Mercat,
    • Jean-Luc Diehl,
    • Jean-Pierre Sollet,
    • Alain Tenaillon,
    • and for the VAP Trial Group*
    Ann Intern Med April 18, 2000 132:621-630

    In patients suspected of having ventilator-associated pneumonia, an invasive diagnostic strategy based on use of fiberoptic bronchoscopy improved the survival rate, decreased antibiotic use, and was associated with earlier attenuation of organ dysfunction compared with a noninvasive strategy.

Brief Communications

  • Potentiation of Vitamin K Antagonists by High-Dose Intravenous Methylprednisolone

    • Nathalie Costedoat-Chalumeau,
    • Zahir Amoura,
    • Guy Aymard,
    • Odile Sevin,
    • Bertrand Wechsler,
    • Patrice Cacoub,
    • Le Thi Huong Du,
    • Bertrand Diquet,
    • Annick Ankri,
    • and Jean-Charles Piette
    Ann Intern Med April 18, 2000 132:631-635

    This study found that the action of oral anticoagulants is potentiated by intravenous high-dose methylprednisolone. The international normalized ratio should be monitored daily during concomitant administration of these medications.

  • The Effect of Coenzyme Q10 in Patients with Congestive Heart Failure

    • Meenakshi Khatta,
    • Barbara S. Alexander,
    • Cathy M. Krichten,
    • Michael L. Fisher,
    • Ronald Freudenberger,
    • Shawn W. Robinson,
    • and Stephen S. Gottlieb
    Ann Intern Med April 18, 2000 132:636-640

    In a randomized, controlled trial, coenzyme Q10 did not affect ejection fraction, peak oxygen consumption, or exercise duration in patients with congestive heart failure receiving standard medical therapy.

Academia and Clinic

  • Education of Physicians-in-Training Can Decrease the Risk for Vascular Catheter Infection

    • Robert J. Sherertz,
    • E. Wesley Ely,
    • Debi M. Westbrook,
    • Kate S. Gledhill,
    • Stephen A. Streed,
    • Betty Kiger,
    • Lenora Flynn,
    • Stewart Hayes,
    • Sallie Strong,
    • Julia Cruz,
    • David L. Bowton,
    • Todd Hulgan,
    • and Edward F. Haponik
    Ann Intern Med April 18, 2000 132:641-648

    Physicians-in-training participated in a course designed to standardize infection control practices. This course proved to be cost-effective and was associated with improved sterile technique and a significantly reduced risk for catheter-related infections.

Updates

  • Gene Therapy for Lung Disease: Hype or Hope?

    • Steven M. Albelda,
    • Rainer Wiewrodt,
    • and Jonathan B. Zuckerman
    Ann Intern Med April 18, 2000 132:649-660

    This Update examines general concepts in gene therapy, summarizes the results of published clinical trials, and highlights areas of research aimed at overcoming challenges in the field.

Review

  • The Lyme Disease Vaccine: Conception, Development, and Implementation

    • Wendy Todaro Thanassi and
    • Robert T. Schoen
    Ann Intern Med April 18, 2000 132:661-668

    The Lyme disease vaccine, approved by the Food and Drug Administration in 1998, is important because it may reduce the morbidity and financial costs associated with Lyme disease. Through the vaccine's unique mechanism, the vaccine works inside the tick vector itself, preventing humans from becoming infected.

Editorials

  • Combating Sloth as Well as Gluttony: The Role of Physical Fitness in Mortality among Men with Type 2 Diabetes

    • Charles M. Clark, Jr.
    Ann Intern Med April 18, 2000 132:669-670

    Wei and colleagues' findings, reported in this issue, remind us that a comprehensive exercise program should be an integral part of diabetes care.

  • On Being a Doctor 2

    • Michael A. LaCombe and
    • Frank Davidoff
    Ann Intern Med April 18, 2000 132:671-672

    The recently published book On Being a Doctor 2: Voices of Physicians and Patients contains the best of the published submissions to the On Being a Doctor, On Being a Patient, and Ad Libitum sections of Annals.

Letters

  • More on Alternative Medicine

    • Michael J. Sergeant
    Ann Intern Med April 18, 2000 132:675

  • More on Alternative Medicine

    • Ted J. Kaptchuk
    Ann Intern Med April 18, 2000 132:675

  • Doctors' Daughter

    • Stephanie Nagy-Agren
    Ann Intern Med April 18, 2000 132:676

  • Standardization of Hemoglobin A1c Values

    • Meera Jain,
    • Anthony McCall,
    • and Matthew Riddle
    Ann Intern Med April 18, 2000 132:676

  • Homocyst(e)ine and Cardiovascular Disease

    • Alan S. Feiner
    Ann Intern Med April 18, 2000 132:676

  • Homocyst(e)ine and Cardiovascular Disease

    • John W. Eikelboom,
    • Eva Lonn,
    • and Salim Yusuf
    Ann Intern Med April 18, 2000 132:676

  • Hyperhomocysteinemia in Hypothyroidism

    • Daniel Weiss
    Ann Intern Med April 18, 2000 132:677

  • Hyperhomocysteinemia in Hypothyroidism

    • Charles Faiman,
    • Donald W. Jacobsen,
    • and Ralph Green
    Ann Intern Med April 18, 2000 132:677

  • Rapid-Onset Subfulminant Liver Failure Associated with Troglitazone

    • Sanjay Jagannath and
    • Rudra Rai
    Ann Intern Med April 18, 2000 132:677

  • Factor VIII Antibodies Developing after a Spider Bite

    • Julio Hajdenberg,
    • Jeffrey Davis,
    • and Roberto Arevalo Araujo
    Ann Intern Med April 18, 2000 132:677-678

  • Cooling Methods for Heatstroke Victims

    • Stephen L. Gaffin,
    • John W. Gardner,
    • and Scott D. Flinn
    Ann Intern Med April 18, 2000 132:678-679

  • Abolished Vagal Tone Associated with Thyrotoxicosis Triggers Prinzmetal Variant Angina and Paroxysmal Atrial Fibrillation

    • Michele Emdin,
    • Lorenza Pratali,
    • and Giorgio Iervasi
    Ann Intern Med April 18, 2000 132:679

  • Cocaine Washout Syndrome

    • James R. Roberts and
    • Michael I. Greenberg
    Ann Intern Med April 18, 2000 132:679-680

  • Use of Bromelain for Mild Ulcerative Colitis

    • Sunanda Kane and
    • Michael J. Goldberg
    Ann Intern Med April 18, 2000 132:680

  • Acute Pancreatitis Associated with Celecoxib

    • Anne M. Baciewicz,
    • Denise R. Sokos,
    • and Thomas J. King
    Ann Intern Med April 18, 2000 132:680

  • Apoptosis in Cardiac Myxoma

    • Makoto Suzuki,
    • Mareomi Hamada,
    • and Kunio Hiwada
    Ann Intern Med April 18, 2000 132:681

  • Propanolol Administration in a Patient with Thyroid Storm

    • Hiroshi Ashikaga,
    • Ricardo Abreu,
    • and Roslyn F. Schneider
    Ann Intern Med April 18, 2000 132:681-682

  • Ischemic Colitis Associated with Decongestant Use

    • Gary R. Lichtenstein and
    • Nelson S. Yee
    Ann Intern Med April 18, 2000 132:682

  • Parvovirus B19 and Glomerulonephritis in a Healthy Adult

    • Matthias L. Schmid,
    • Paul H. M. McWhinney,
    • and Es J. Will
    Ann Intern Med April 18, 2000 132:682

Medical Writings: Book Notes

Currents

  • Conference Roundup: HIV and AIDS

    • Brigid Kane
    Ann Intern Med April 18, 2000 132:685

  • The Invisible Hand of the Government in Medical Education

    • Paul T. Kefalides
    Ann Intern Med April 18, 2000 132:686

Ad Libitum

Book Listings

Medical Notices

  • Medical Notices

    Ann Intern Med April 18, 2000 132:0

Summaries for Patients

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This Issue

April 18, 2000; 132 (8)
  1. Articles
  2. Brief Communications
  3. Academia and Clinic
  4. Updates
  5. Review
  6. Editorials
  7. Letters
  8. Medical Writings: Book Notes
  9. Currents
  10. Ad Libitum
  11. Book Listings
  12. Medical Notices
  13. Summaries for Patients

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