Table of Contents

March 7, 2000; 132 (5)

Articles

  • Dizziness among Older Adults: A Possible Geriatric Syndrome

    • Mary E. Tinetti,
    • Christianna S. Williams,
    • and Thomas M. Gill
    Ann Intern Med March 7, 2000 132:337-344

    According to this study, the association among characteristics in several domains (including cardiovascular and neurologic) and dizziness, coupled with the multiplicity of sensations and triggering activities, suggests that dizziness may be a geriatric syndrome. If so, an impairment reduction strategy may be effective in reducing the symptoms and disabilities associated with dizziness.

  • Low Fractional Calcium Absorption Increases the Risk for Hip Fracture in Women with Low Calcium Intake

    • Kristine E. Ensrud,
    • Tu Duong,
    • Jane A. Cauley,
    • Robert P. Heaney,
    • Randi L. Wolf,
    • Emily Harris,
    • Steven R. Cummings,
    • and for the Study of Osteoporotic Fractures Research Group*
    Ann Intern Med March 7, 2000 132:345-353

    In the elderly women in this study, low fractional calcium absorption in the setting of low calcium intake increased the risk for hip fracture. These findings support the hypothesis of type II osteoporosis, which postulates that decreased calcium absorption is an important risk factor for hip fracture in older persons.

  • Effects of Fexofenadine, Diphenhydramine, and Alcohol on Driving Performance: A Randomized, Placebo-Controlled Trial in the Iowa Driving Simulator

    • John M. Weiler,
    • John R. Bloomfield,
    • George G. Woodworth,
    • Angela R. Grant,
    • Teresa A. Layton,
    • Timothy L. Brown,
    • David R. McKenzie,
    • Thomas W. Baker,
    • and Ginger S. Watson
    Ann Intern Med March 7, 2000 132:354-363

    Previous studies suggest that sedating antihistamines may impair driving performance as much as alcohol does. The participants in this study had similar simulated driving performance when treated with fexofenadine (a nonsedating drug) or placebo. After alcohol use, participants performed the primary task (matching the varying speed of a vehicle they were following) well but not secondary tasks. After participants received diphenhydramine (a sedating drug), driving performance was poorest, indicating that this drug had a greater effect on driving than alcohol did.

Brief Communications

  • Recombinant Human Thrombopoietin Attenuates Carboplatin-Induced Severe Thrombocytopenia and the Need for Platelet Transfusions in Patients with Gynecologic Cancer

    • Saroj Vadhan-Raj,
    • Claire F. Verschraegen,
    • Carlos Bueso-Ramos,
    • Hal E. Broxmeyer,
    • Andrzej P. Kudelka,
    • Ralph S. Freedman,
    • Creighton L. Edwards,
    • David Gershenson,
    • Dennie Jones,
    • Mark Ashby,
    • and John J. Kavanagh
    Ann Intern Med March 7, 2000 132:364-368

    In patients with gynecologic cancer, therapy with recombinant human thrombopoietin seems to be safe, may attenuate chemotherapy-induced severe thrombocytopenia, and may reduce the need for platelet transfusions.

  • Increased Susceptibility to Pulmonary Emphysema among HIV-Seropositive Smokers

    • Philip T. Diaz,
    • Mark A. King,
    • Eric R. Pacht,
    • Mark D. Wewers,
    • James E. Gadek,
    • Haikady N. Nagaraja,
    • Janice Drake,
    • and Thomas L. Clanton
    Ann Intern Med March 7, 2000 132:369-372

    Infection with HIV accelerates the onset of smoking-induced emphysema. The results of this study support the emerging concept that cytotoxic lymphocytes may be important in the pathogenesis of emphysema.

Academia and Clinic

  • Developing and Implementing Computerized Protocols for Standardization of Clinical Decisions

    • Alan H. Morris
    Ann Intern Med March 7, 2000 132:373-383

    The mismatch between human memory limitation and excess information almost certainly contributes to the unnecessary variation in clinical practice and to clinical error. This paper considers the problems created by this mismatch and describes a computer-based decision-support system that successfully combines rules based on credible evidence with specific data from individual patients.

Review

  • Prevention of Intravascular Catheter–Related Infections

    • Leonard A. Mermel
    Ann Intern Med March 7, 2000 132:391-402

    Several studies have shown that attention to simple and practical interventions reduces the risk for intravascular catheter–related bloodstream infections. This review updates the expanding body of literature on the prevention of these infections.

Position Papers

  • Responding to Intractable Terminal Suffering: The Role of Terminal Sedation and Voluntary Refusal of Food and Fluids

    • Timothy E. Quill,
    • Ira R. Byock,
    • and for the ACP-ASIM End-of-Life Care Consensus Panel
    Ann Intern Med March 7, 2000 132:408-414

    This paper presents terminal sedation and voluntary refusal of hydration and nutrition as potential measures of last resort that can be used to address the needs of certain patients with terminal illness. These methods substantially increase patients' choices at an inherently challenging period of illness.

Editorials

  • Occam's Razor, Geriatric Syndromes, and the Dizzy Patient

    • David A. Drachman
    Ann Intern Med March 7, 2000 132:403-405

    Tinetti and colleagues' study in this issue emphasizes an important and easily forgotten point: Dizziness, especially among elderly persons, is often due to multiple disorders involving multiple organ systems. This geriatric syndrome requires—and deserves—careful attention to sort out the underlying diagnoses and institute successful treatment.

  • Nonsedating Antihistamines Should Be Preferred over Sedating Antihistamines in Patients Who Drive

    • Sean Hennessy and
    • Brian L. Strom
    Ann Intern Med March 7, 2000 132:405-407

    The study by Weiler and colleagues in this issue highlights the importance of determining the possible differential effects of sedating compared with nonsedating antihistamines on driving performance and the risk for motor vehicle crashes.

Letters

  • Trends in Tuberculosis Transmission

    • Richard J. Blinkhorn, Jr
    Ann Intern Med March 7, 2000 132:416

  • Trends in Tuberculosis Transmission

    • Robert M. Jasmer,
    • Charles L. Daley,
    • and Philip C. Hopewell
    Ann Intern Med March 7, 2000 132:416-417

  • Mycophenolate Mofetil-Induced Dyshidrotic Eczema

    • Sylvie Semhoun-Ducloux,
    • Didier Ducloux,
    • and Jean-Philippe Miguet
    Ann Intern Med March 7, 2000 132:417

  • Venlafaxine-Associated Hepatitis

    • Xavier Cardona,
    • Asunción Avila,
    • and Pere Castellanos
    Ann Intern Med March 7, 2000 132:417

  • Hydroxyurea-Induced Leg Ulcers Treated with Apligraf

    • Francisco Flores,
    • William A. Eaglstein,
    • and Robert S. Kirsner
    Ann Intern Med March 7, 2000 132:417-418

  • Understanding Adherence to HIV Medication

    • Jason M. Leider and
    • Gary Kalkut
    Ann Intern Med March 7, 2000 132:418

  • Importance of Proper Identification of Stinging Insects

    • H.C. George Wong
    Ann Intern Med March 7, 2000 132:418

  • Use of Statins and Fibrates in Hyperlipidemic Patients with Neuromuscular Disorders

    • Nathalie M. Leung,
    • Teik Chye Ooi,
    • and Matthew J. McQueen
    Ann Intern Med March 7, 2000 132:418-419

  • Correction: Preference for Site of Terminal Care

    Ann Intern Med March 7, 2000 132:419

  • Correction: Pancreatic Dysplasia

    Ann Intern Med March 7, 2000 132:419

Medical Writings

  • Richard Lower: Anatomist and Physiologist

    • John H. Felts
    Ann Intern Med March 7, 2000 132:420-423

    A student of Thomas Willis, Richard Lower was part of a revival of the Oxford school of physiology in the mid-1600s. Among his many accomplishments were performing the first-ever blood transfusion in animals and the first transfusion in a human in England. He devised the apparatus for maintaining vascular access for cross-circulation and for administration of drugs, blood, and other fluids, from which many of our modern procedures and devices derive.

Medical Writings: Book Notes

Book Listings

Medical Notices

  • Medical Notices

    Ann Intern Med March 7, 2000 132:0

Summaries for Patients

Updates from the Annual Session

  • Update in Hospital Medicine

    • Franklin A. Michota, Jr
    Ann Intern Med March 7, 2000 132:384-390

    This Update discusses four areas relevant to the care of hospitalized patients: nosocomial illness, community-acquired pneumonia, deep venous thrombosis, and prognostic variables.

« Previous | Next Issue »

This Issue

March 7, 2000; 132 (5)
  1. Articles
  2. Brief Communications
  3. Academia and Clinic
  4. Review
  5. Position Papers
  6. Editorials
  7. Letters
  8. Medical Writings
  9. Medical Writings: Book Notes
  10. Book Listings
  11. Medical Notices
  12. Summaries for Patients
  13. Updates from the Annual Session

Search in this issue:

Current Issue

  1. November 3, 2009, 151 (9)
  1. Alert me to current issues