Table of Contents

November 2, 1999; 131 (9)

Articles

  • Clinical Utility of Blood Cultures Drawn from Indwelling Central Venous Catheters in Hospitalized Patients with Cancer

    • Jeffrey A. DesJardin,
    • Matthew E. Falagas,
    • Robin Ruthazer,
    • John Griffith,
    • Dorothy Wawrose,
    • David Schenkein,
    • Kenneth Miller,
    • and David R. Snydman
    Ann Intern Med November 2, 1999 131:641-647

    In hospitalized hematology–oncology patients, culture of blood drawn through a central catheter or peripheral vein has excellent negative predictive value. Culture of blood drawn through an indwelling central venous catheter has a low positive predictive value, apparently less than seen with peripheral venipuncture. Thus, a positive result from a catheter needs clinical interpretation and may require confirmation. However, use of a catheter to obtain blood for culture may be acceptable for ruling out bloodstream infections.

  • Early β-Blocker Therapy for Acute Myocardial Infarction in Elderly Patients

    • Harlan M. Krumholz,
    • Martha J. Radford,
    • Yun Wang,
    • Jersey Chen,
    • and Thomas A. Marciniak
    Ann Intern Med November 2, 1999 131:648-654

    In this study, early β-blocker therapy was not used for 51% of elderly patients who were hospitalized with an acute myocardial infarction and did not have a contraindication to this therapy. Increasing β-blocker use for these patients would provide an excellent opportunity to improve their care and outcomes.

  • Is History of Squamous-Cell Skin Cancer a Marker of Poor Prognosis in Patients with Cancer?

    • Johan Askling,
    • Per Sørensen,
    • Anders Ekbom,
    • Morten Frisch,
    • Mads Melbye,
    • Bengt Glimelius,
    • and Henrik Hjalgrim
    Ann Intern Med November 2, 1999 131:655-659

    Patients with a history of squamous-cell skin cancer have a worse prognosis after diagnosis of subsequent cancer than patients without prior skin cancer, and they warrant careful medical attention.

  • The Cost-Effectiveness of Treating All Patients with Type 2 Diabetes with Angiotensin-Converting Enzyme Inhibitors

    • Lubor Golan,
    • John D. Birkmeyer,
    • and H. Gilbert Welch
    Ann Intern Med November 2, 1999 131:660-667

    Treating all middle-aged diabetic patients with angiotensin-converting enzyme inhibitors is a simple strategy that provides additional benefit at modest additional cost. The strategy assumes that patients meet the older diagnostic criteria for diabetes and makes sense only for patients who are not bothered by the treatment.

Brief Communications

  • Reversal of Iron Deficiency Anemia after Helicobacter pylori Eradication in Patients with Asymptomatic Gastritis

    • Bruno Annibale,
    • Massimo Marignani,
    • Bruno Monarca,
    • Giorgio Antonelli,
    • Adriana Marcheggiano,
    • Gina Martino,
    • Franco Mandelli,
    • Renzo Caprilli,
    • and Gianfranco Delle Fave
    Ann Intern Med November 2, 1999 131:668-672

    Cure of Helicobacter pylori infection is associated with reversal of iron dependence and recovery from iron deficiency anemia.

Academia and Clinic

  • Noninvasive Imaging for the Diagnosis of Coronary Artery Disease: Focusing the Development of New Diagnostic Technology

    • Maria G.M. Hunink,
    • Karen M. Kuntz,
    • Kirsten E. Fleischmann,
    • and Thomas J. Brady
    Ann Intern Med November 2, 1999 131:673-680

    New imaging techniques, such as magnetic resonance imaging and electron-beam computed tomography, must be relatively inexpensive and have excellent sensitivity and specificity to be cost-effective compared with other techniques that are already available for the diagnosis of coronary artery disease.

Updates

  • Atrial Fibrillation and Thromboembolism: A Decade of Progress in Stroke Prevention

    • Robert G. Hart and
    • Jonathan L. Halperin
    Ann Intern Med November 2, 1999 131:688-695

    The remarkable pace of development has revolutionized management of nonvalvular atrial fibrillation and makes detection of this long-neglected dysrhythmia an important opportunity for stroke prevention. This paper presents recent advances, discusses controversies, and explores new ideas about stroke and its prevention in patients with nonvalvular atrial fibrillation.

Perspectives

  • Use of Interferon for Prevention of Hepatocellular Carcinoma in Cirrhotic Patients with Hepatitis B or Hepatitis C Virus Infection

    • Vicky Baffis,
    • Ian Shrier,
    • Averell H. Sherker,
    • and Andrew Szilagyi
    Ann Intern Med November 2, 1999 131:696-701

    This paper discusses the pathogenesis of hepatocellular carcinoma in patients with cirrhosis related to hepatitis B or C and reviews clinical studies of interferon therapy to prevent or delay hepatocellular carcinoma in these patients.

History of Medicine

  • Henry Harrower and the Turbulent Beginnings of Endocrinology

    • Theodore B. Schwartz
    Ann Intern Med November 2, 1999 131:702-706

    In the mid- to late 19th century, the schism between academicians and medical practitioners was nowhere greater than in the field of endocrinology. Henry Harrower was a leading proponent of organotherapeutics—the idea that extracts from glands were effective for treating most human ailments. This school of thought went unchallenged for years until Harvey Cushing launched an attack on its purveyors.

Editorial

  • Interpreting, Integrating, and Individualizing Evidence about the Prevention of Diabetic Nephropathy

    • Deborah J. Cook and
    • Gordon H. Guyatt
    Ann Intern Med November 2, 1999 131:707-708

    Golan and colleagues' decision analysis in this issue focuses on the prevention of diabetic neuropathy under three scenarios. This study highlights the reality that clinicians and patients with different perspectives and resources might come to different conclusions when presented with the same evidence about a screening procedure.

On Being a Doctor

  • Harry James

    • Leslie G. Cohen
    Ann Intern Med November 2, 1999 131:710-711

    A trumpet-playing 13-year-old patient evokes memories of a doctor's own musical—and medical—ambitions.

Letters

  • Famciclovir and Postherpetic Neuralgia

    • Ken L. Bassett,
    • Carolyn J. Green,
    • and James M. Wright
    Ann Intern Med November 2, 1999 131:712

  • Famciclovir and Postherpetic Neuralgia

    • Stephen Tyring,
    • Robin L. Saltzman,
    • and Robert Dworkin
    Ann Intern Med November 2, 1999 131:712-713

  • Theophylline Therapy for Near-Fatal Cheyne-Stokes Respiration

    • Don D. Sin and
    • T. Douglas Bradley
    Ann Intern Med November 2, 1999 131:713

  • Theophylline Therapy for Near-Fatal Cheyne-Stokes Respiration

    • Edgar J. Geigel and
    • Alejandro D. Chediak
    Ann Intern Med November 2, 1999 131:713-714

  • Theophylline Therapy for Near-Fatal Cheyne-Stokes Respiration

    • Virend K. Somers and
    • Catherine Pesek
    Ann Intern Med November 2, 1999 131:714

  • Improving Preventive Care Guidelines

    • Keith W. Roach
    Ann Intern Med November 2, 1999 131:714-715

  • Improving Preventive Care Guidelines

    • Scott Weingarten
    Ann Intern Med November 2, 1999 131:715

  • Elevated Estradiol and Testosterone Levels and Risk for Breast Cancer

    • Herbert Yu,
    • Eleftherios P. Diamandis,
    • and Barry Hoffman
    Ann Intern Med November 2, 1999 131:715

  • Delayed Treatment of Bacterial Meningitis

    • James R. Johnson
    Ann Intern Med November 2, 1999 131:715

  • Impaired Glucose Tolerance in HIV-Infected Patients

    • Zuhayr T. Madhun,
    • Baha M. Arafah,
    • and Grace A. McComsey
    Ann Intern Med November 2, 1999 131:715-716

  • Treatment of Chronic Lead Intoxication

    • Ana I. Sanchez-Fructuoso,
    • Dolores Prats,
    • and Alberto Barrientos
    Ann Intern Med November 2, 1999 131:716

  • Hepatitis B Virus Genotypic Resistance to Lamivudine

    • Hélène Fontaine,
    • Valérie Thiers,
    • and Stanislas Pol
    Ann Intern Med November 2, 1999 131:716-717

  • Left Coronary Ostial Stenosis Caused by Focal Intimal Fibrosis

    • Afksendiyos Kalangos
    Ann Intern Med November 2, 1999 131:717

  • Correction: Nathan Smith and Early American Education

    Ann Intern Med November 2, 1999 131:717

Medical Writings

  • W; t

    • Faith McLellan
    Ann Intern Med November 2, 1999 131:718-719

    The Pulitzer Prize–winning play W;t captures some hard truths about the experience of illness, while at the same time reflecting a long and sometimes distinguished tradition of illness narratives, or pathographies.

Medical Writings: Book Notes

  • Clinical Practice of Gastroenterology

    • Tony M. Balistreri and
    • William F. Balistreri
    Ann Intern Med November 2, 1999 131:720

  • Contagion and Confinement: Controlling Tuberculosis along the Skid Road

    • William W. Stead
    Ann Intern Med November 2, 1999 131:720

Ad Libitum

Book Listings

Medical Notices

  • Medical Notices

    Ann Intern Med November 2, 1999 131:0

Summaries for Patients

  • Are Blood Tests for Infection Accurate If They are Taken from Patients' Intravenous Lines?

    Ann Intern Med November 2, 1999 131:641

  • Beta-blocker Medicines for Older People after Heart Attack

    Ann Intern Med November 2, 1999 131:648

  • The Outlook in Cancer Patients Who Previously Had Skin Cancer

    Ann Intern Med November 2, 1999 131:655

  • The Costs of Preventing Kidney Failure in People with Diabetes

    Ann Intern Med November 2, 1999 131:660

  • Treating Helicobacter pylori Infection May Improve Anemia

    Ann Intern Med November 2, 1999 131:668

Updates from the Annual Session

  • Update in Preventive Medicine

    • Laurence H. Beck and
    • Seema Pania Kumar
    Ann Intern Med November 2, 1999 131:681-687

    Many of the studies published in 1998 that dealt with prevention are concentrated in three areas: cardiovascular disease, breast and other cancers, and osteoporosis.

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This Issue

November 2, 1999; 131 (9)
  1. Articles
  2. Brief Communications
  3. Academia and Clinic
  4. Updates
  5. Perspectives
  6. History of Medicine
  7. Editorial
  8. On Being a Doctor
  9. Letters
  10. Medical Writings
  11. Medical Writings: Book Notes
  12. Ad Libitum
  13. Book Listings
  14. Medical Notices
  15. Summaries for Patients
  16. Updates from the Annual Session

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