The Stiff-Person Syndrome: An Autoimmune Disorder Affecting Neurotransmission of γ-Aminobutyric Acid

Figure 4. The signal profile represents the magnitude of the metabolite peaks occurring in a two-dimensional J-resolved spectrum along the J = 0 axis, where J is the decoupling dimension variable. Decoupling of peaks by introduction of a second dimension improves separation and identification of metabolite peaks. GABA = γ-aminobutyric acid; NAA = -acetylaspartate.
Figure 4. The signal profile represents the magnitude of the metabolite peaks occurring in a two-dimensional J-resolved spectrum along the J = 0 axis, where J is the decoupling dimension variable. Decoupling of peaks by introduction of a second dimension improves separation and identification of metabolite peaks. GABA = γ-aminobutyric acid; NAA = -acetylaspartate. Two-dimensional J-resolved spectroscopy plot of the sensorimotor cortex of a patient with the stiff-person syndrome.N

This Article

  1. Ann Intern Med October 5, 1999 vol. 131 no. 7 522-530
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