Long-Term Sequelae of Spontaneous Axillary–Subclavian Venous Thrombosis

Abstract

Background: The frequency and severity of post-thrombotic sequelae after spontaneous axillary–subclavian venous thrombosis remain poorly known.

Objective: To determine the late sequelae of conventionally treated spontaneous axillary–subclavian venous thrombosis.

Design: Cross-sectional study.

Setting: University department of vascular medicine.

Patients: 54 patients seen during an 18-year period (mean follow-up, 5 years).

Measurements: Scores for the severity of post-thrombotic symptoms were graded on a numerical rating scale ranging from 0 to 10 and on a 6-point verbal rating scale. Ultrasonographic sequelae were classified as grade 0, normal flow; grade 1, moderate obstruction; or grade 2, severe obstruction or occlusion.

Results: Verbal scores were “nil/negligible” in 47% of patients and “severe/intolerable” in 13%; numerical scores were 0 to 3 in 78% of patients and 7 to 10 in 9%. Grade 2 ultrasonographic sequelae were found in 22% of cases. No relation was seen between ultrasonographic sequelae and symptom severity scores.

Conclusion: The overall clinical outcome of spontaneous axillary–subclavian venous thrombosis is good, and there is no relation between the severity of late symptoms and ultrasonographic sequelae.