Serum Total Homocysteine Concentrations in the Third National Health and Nutrition Examination Survey (1991–1994): Population Reference Ranges and Contribution of Vitamin Status to High Serum Concentrations

  1. Jacob Selhub, PhD;
  2. Paul F. Jacques, ScD;
  3. Irwin H. Rosenberg, MD;
  4. Gail Rogers, BA;
  5. Barbara A. Bowman, PhD;
  6. Elaine W. Gunter, MT;
  7. Jacqueline D. Wright, MPH; and
  8. Clifford L. Johnson, MSPH
  1. From Tufts University, Boston, Massachusetts; and Centers for Disease Control and Prevention, Hyattsville, Maryland, and Atlanta, Georgia.
    1. Figure 1. Mean homocysteine concentrations are plotted at the median folate value within each decile category. Lines represent the smoothed trend of the geometric mean across decile category. Bars represent 95% CIs.
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      Figure 1. Mean homocysteine concentrations are plotted at the median folate value within each decile category. Lines represent the smoothed trend of the geometric mean across decile category. Bars represent 95% CIs. Geometric mean serum total homocysteine concentrations by decile category of serum folate concentration for male participants (circles) and female participants (squares) 12 to 19 years of age (top left), 20 to 39 years of age (top right), 40 to 59 years of age (bottom left), and 60 years of age or older (bottom right).
    2. Figure 2. Mean homocysteine concentrations are plotted at the median vitamin B value within each decile category. Lines represent the smoothed trend of the geometric mean across decile categories. Bars represent 95% CIs.
      View larger version:
      Figure 2. Mean homocysteine concentrations are plotted at the median vitamin B value within each decile category. Lines represent the smoothed trend of the geometric mean across decile categories. Bars represent 95% CIs. Geometric mean serum total homocysteine concentrations by decile category of serum vitamin B 12 concentration for male participants (circles) and female participants (squares) 12 to 19 years of age (top left), 20 to 39 years of age (top right), 40 to 59 years of age (bottom left), and 60 years of age or older (bottom right).12
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    1. Ann Intern Med September 7, 1999 vol. 131 no. 5 331-339
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