Adrenocortical Tumors: Recent Advances in Basic Concepts and Clinical Management

Figure 4. For the diagnosis of primary hypercortisolism, this algorithm suggests tests that are used for screening, confirmation,
and localization of a cortisol-producing or corticotropin ( )-producing tumor. To convert serum cortisol values to nmol/L
and to convert urine free cortisol values to nmol/d, multiply by 2.759. If there is more than one item, follow the respective
numbers throughout the algorithm. BIPSS = bilateral inferior petrosal sinus sampling (measurement of plasma corticotropin
concentrations in the inferior petrosal sinuses and a peripheral vein ); CRH = corticotropin-releasing hormone; CT = computed
tomography; MRI = magnetic resonance imaging.
Diagnostic algorithm for the Cushing syndrome.ACTH[114]
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Ann Intern Med
May 4, 1999
vol. 130
no. 9
759-771