Adrenocortical Tumors: Recent Advances in Basic Concepts and Clinical Management

Figure 2. Adrenal nodules ( ) originating within the adrenal medulla ( ). Medullary cells are stained with an antibody to chromogranin A (original magnification, ×60). Lymphocytic infiltration in a cortisol-producing adrenal adenoma causing the Cushing syndrome. Lymphocytes characterized with antibodies to CD45 (Clone 2B 11, Dako, Copenhagen, Denmark) are in direct contact with adrenal tumor cells. No signs of autoimmune disease or inflammation were seen in this patient. The reaction was visualized with 3-amino-ethylcarbasole (original magnification, ×200). C = cortex.
Figure 2. Adrenal nodules ( ) originating within the adrenal medulla ( ). Medullary cells are stained with an antibody to chromogranin A (original magnification, ×60). Lymphocytic infiltration in a cortisol-producing adrenal adenoma causing the Cushing syndrome. Lymphocytes characterized with antibodies to CD45 (Clone 2B 11, Dako, Copenhagen, Denmark) are in direct contact with adrenal tumor cells. No signs of autoimmune disease or inflammation were seen in this patient. The reaction was visualized with 3-amino-ethylcarbasole (original magnification, ×200). C = cortex. Immunostaining of specimens of adrenal adenoma. A.NODMB.

This Article

  1. Ann Intern Med May 4, 1999 vol. 130 no. 9 759-771
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