An Inherited Disorder of Lymphocyte Apoptosis: The Autoimmune Lymphoproliferative Syndrome

Figure 3. Cell loss is the fraction of cycling T cells lost after 24 hours of Fas cross-linking by an agonistic monoclonal antibody. Shown are the results obtained by using cycling T cells from normal controls ( ) and seven unrelated patients with ALPS ( ).
Figure 3. Cell loss is the fraction of cycling T cells lost after 24 hours of Fas cross-linking by an agonistic monoclonal antibody. Shown are the results obtained by using cycling T cells from normal controls ( ) and seven unrelated patients with ALPS ( ). Apoptosis after Fas (CD95) stimulation is impaired in patients with the autoimmune lymphoproliferative syndrome (ALPS).NormPt

This Article

  1. Ann Intern Med April 6, 1999 vol. 130 no. 7 591-601
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