Table of Contents

April 6, 1999; 130 (7)

Articles

  • Use of Hormone Replacement Therapy by Postmenopausal Women in the United States

    • Nancy L. Keating,
    • Paul D. Cleary,
    • Alice S. Rossi,
    • Alan M. Zaslavsky,
    • and John Z. Ayanian
    Ann Intern Med April 6, 1999 130:545-553

    Sociodemographic factors, such as region and education, may be more strongly associated with use of hormone replacement therapy than are clinical factors, such as risk for cardiovascular disease.

  • The Effect of Dietary ω-3 Fatty Acids on Coronary Atherosclerosis: A Randomized, Double-Blind, Placebo-Controlled Trial

    • Clemens von Schacky,
    • Peter Angerer,
    • Wolfgang Kothny,
    • Karl Theisen,
    • and Harald Mudra
    Ann Intern Med April 6, 1999 130:554-562

    Dietary intake of ω-3 fatty acids modestly mitigates the course of coronary atherosclerosis in humans.

  • Depressive Symptoms and 3-Year Mortality in Older Hospitalized Medical Patients

    • Kenneth E. Covinsky,
    • Eva Kahana,
    • Marshall H. Chin,
    • Robert M. Palmer,
    • Richard H. Fortinsky,
    • and C. Seth Landefeld
    Ann Intern Med April 6, 1999 130:563-569

    Depressive symptoms are associated with long-term mortality in older patients hospitalized with medical illnesses. This association is not fully explained by greater levels of comorbid illness, functional impairment, and cognitive impairment in patients with more symptoms of depression.

  • Relations among CD4 Lymphocyte Count Nadir, Antiretroviral Therapy, and HIV-1 Disease Progression: Results from the EuroSIDA Study

    • Veronica Miller,
    • Amanda Mocroft,
    • Peter Reiss,
    • Christine Katlama,
    • Anthony I. Papadopoulos,
    • Terese Katzenstein,
    • Jan van Lunzen,
    • Francisco Antunes,
    • Andrew N. Phillips,
    • Jens D. Lundgren,
    • and for the EuroSIDA Study Group*
    Ann Intern Med April 6, 1999 130:570-577

    Increases in CD4 counts from very low levels to at least 200 cells/mm3 are associated with a reduced rate of disease progression. However, a previously low CD4 cell count nadir remains associated with a moderately high risk for disease progression among patients with CD4 cell counts of at least 200 cells/mm3.

Brief Communications

  • Arterial Endothelial Dysfunction Related to Passive Smoking Is Potentially Reversible in Healthy Young Adults

    • Olli T. Raitakari,
    • Mark R. Adams,
    • Robyn J. McCredie,
    • Kaye A. Griffiths,
    • and David S. Celermajer
    Ann Intern Med April 6, 1999 130:578-581

    In healthy young adults, arterial endothelial dysfunction related to passive smoking seems to be partially reversible.

  • Cardiac Asystole and Bradycardia as a Manifestation of Left Temporal Lobe Complex Partial Seizure

    • Eduardo R. Locatelli,
    • Jacob P. Varghese,
    • Ashfaq Shuaib,
    • and Samuel J. Potolicchio
    Ann Intern Med April 6, 1999 130:581-583

    This report describes three patients with asystole or bradycardia associated with complex partial seizures and reviews the relevant literature.

Updates

  • Acute Heroin Overdose

    • Karl A. Sporer
    Ann Intern Med April 6, 1999 130:584-590

    This Update reviews the clinically relevant pharmacology of heroin and naloxone, the epidemiology of fatal and nonfatal heroin overdose, the clinical diagnosis of heroin overdose, appropriate treatment, complications, and prevention strategies.

NIH Conferences

  • An Inherited Disorder of Lymphocyte Apoptosis: The Autoimmune Lymphoproliferative Syndrome

    • Stephen E. Straus,
    • Michael Sneller,
    • Michael J. Lenardo,
    • Jennifer M. Puck,
    • and Warren Strober
    Ann Intern Med April 6, 1999 130:591-601

    The autoimmune lymphoproliferative syndrome is a recently defined illness that arises in early childhood and is associated with prominent nonmalignant lymphadenopathy, hepatosplenomegaly, and autoimmune manifestations. This syndrome affords novel insights into the mechanisms that regulate lymphocyte homeostasis and underlie the development of autoimmunity.

Editorials

  • Medical Uncertainty and Practice Variation Get Personal: What Should I Do about Hormone Replacement Therapy?

    • Jennifer Daley
    Ann Intern Med April 6, 1999 130:602-604

    The results of Keating and colleagues' study, reported in this issue, suggest that we may have many more questions to ask and answer about our female patients and how we collaborate with them to find out whether they should use hormone replacement therapy.

  • Probability at the Bedside: The Knowing of Chances or the Chances of Knowing?

    • Steven N. Goodman
    Ann Intern Med April 6, 1999 130:604-606

    As highlighted by Steiner's paper in this issue, evidence-based medicine must grapple with the fact that in the individual patient, one of its pillars—probability—is ambiguous and elusive, no matter how we choose to communicate it.

  • Increasing Organ Donation in the African-American Community: Altruism in the Face of an Untrustworthy System

    • Laura A. Siminoff and
    • Robert Arnold
    Ann Intern Med April 6, 1999 130:607-609

    The shortage of transplantable organs hits the African-American community disproportionately hard. What is responsible for this shortage, and what can be done about it?

On Being a Doctor

  • A Good Pair of Hands

    • Bhuvana Chandra
    Ann Intern Med April 6, 1999 130:610-611

    He greeted me as he always did, hands folded weakly together in the gesture of respect that is ubiquitous in India.

Letters

Medical Writings: Lingua Medica

  • Talking about Treatment: The Language of Populations and the Language of Individuals

    • John F. Steiner
    Ann Intern Med April 6, 1999 130:618-622

    As physicians, we need to become bilingual—we must speak the language of populations as well as the language of individual patients. If we are fluent in both languages, we remind ourselves that we offer our patients choices, not treatments, and we remind our patients that whatever their treatment choices, the outcomes of health care are uncertain.

Medical Writings: Book Notes

Ad Libitum

Book Listings

Medical Notices

  • Medical Notices

    Ann Intern Med April 6, 1999 130:0
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This Issue

April 6, 1999; 130 (7)
  1. Articles
  2. Brief Communications
  3. Updates
  4. NIH Conferences
  5. Editorials
  6. On Being a Doctor
  7. Letters
  8. Medical Writings: Lingua Medica
  9. Medical Writings: Book Notes
  10. Ad Libitum
  11. Book Listings
  12. Medical Notices

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