Urinary Tract Infection with Enterococcus faecalis

  1. George A. Jacoby, MD
  1. Lahey Clinic, Burlington, MA 01805. Graduate Hospital, Philadelphia, PA 19146. Philadelphia Department of Public Health, Philadelphia, PA 19146.

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    TO THE EDITOR:

    Fraimow and colleagues [1] report the first instance of a vancomycin-dependent organism but not the first example of a clinical isolate that required an antimicrobial agent for growth. In 1955, Finland [2] reviewed reports of clinical isolates, including tubercle bacilli, that needed streptomycin for growth. In one report, the condition of a patient with a streptomycin-dependent strain detected in the urine worsened when therapy with streptomycin was resumed after being discontinued for several days. In the laboratory, bacteria dependent on chloramphenicol [2], erythromycin [3], penicillin [2], rifampin [4], and spectinomycin [5] have been obtained. The discovery of vancomycin-dependent strains should inspire a broader search for bacteria requiring other antibiotics in unexpectedly sterile clinical material.

    George A. Jacoby

    The Editors welcome submissions for possible publication in the Letters section. Authors of letters should:

    •Include no more than 300 words of text, three authors, and five references

    •Type with double-spacing

    •Send three copies of the letter, an authors' form signed by all authors, and a cover letter describing any conflicts of interest related to the contents of the letter.

    Letters commenting on an Annals article will be considered if they are received within 6 weeks of the time the article was published. Only some of the letters received can be published. Published letters are edited and may be shortened; tables and figures are included only selectively. Authors will be notified that the letter has been received. If the letter is selected for publication, the author will be notified about 3 weeks before the publication date. Unpublished letters cannot be returned.

    Annals welcomes electronically submitted letters.

    References

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