Preserving Renal Function in Patients with Membranous Nephropathy: Daily Oral Chlorambucil Compared with Intermittent Monthly
Pulses of Cyclophosphamide

Figure 1. Treatment was started at t = 0 months. * = start of renal replacement therapy; Triangle = start of retreatment with
immunosuppressive therapy. The Y-axis represents the reciprocal of serum creatinine ÷ 1000. This ratio reflects renal function.
Renal function as shown by 1000/serum creatinine level in individual patients treated with chlorambucil, methylprednisolone,
and prednisone.
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Ann Intern Med
September 1, 1994
vol. 121
no. 5
328-333