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Pseudoephedrine Reaction Presenting as Recurrent Toxic Shock Syndrome
- From the University of Iowa College of Medicine, Iowa City, Iowa. Requests for Reprints: Zuhair K. Ballas, MD, Department of Internal Medicine, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242-1081. Acknowledgments: The authors thank Gary Beck for editorial and moral support.
Adverse drug reactions are common and can have many clinical manifestations [1]. Some of these reactions, such as the IgE-mediated reactions and the maculopapular rashes, are readily recognized as drug related. Other reactions, such as aseptic meningitis [2] or myocarditis [3], require a high index of suspicion for a drug-related cause. We describe a patient who had an adverse reaction to pseudoephedrine. Symptoms were the same as those seen in recurrent toxic shock syndrome.
Case Report
An 18-year-old woman was referred for evaluation of a possible immunodeficiency causing recurrent toxic shock syndrome. Her problems began in August 1988 when she had a sore throat, nasal congestion, and a low-grade fever followed by development of a punctate, macular erythematous rash on her neck, wrists, and forearms. This rash progressed rapidly to confluent erythema over the trunk and extremities, including the palms and soles. She also developed angioedema of the hands and face, a …
This 100-word excerpt has been provided in the absence of an abstract.
