Reviews, Notes, and Listings: Genetics: Mendelian Inheritance in Man: Catalogs of Autosomal Dominant, Autosomal Recessive, and X-Linked Phenotypes

Mendelian Inheritance in Man: Catalogs of Autosomal Dominant, Autosomal Reeessive, and X-linked Phenotypes. Tenth edition. Two volumes.

Victor A. McKusick. 2320 pages. Baltimore: The Johns Hopkins University Press; 1992. $150.00.

The exuberant growth of clinical genetics and gene mapping accounts for the tenth two-volume edition of Dr. McKusick's invaluable catalog. The kind of content and its arrangement are essentially the same as in the preceding editions: a detailed introduction that should be read by all potential users of the catalog; lists, tables, and graphic summaries of mendelian disorders representing molecular defects, gene symbols and their titles, gene maps of the autosomes and the X and Y chromosomes, available cell lines, and other data; and the short descriptive articles on the cataloged phenotypes that comprise the body of the catalog. The references appended to each article are mainly those relevant to the genetics and cytogenetics of each phenotype, but a sufficient number of papers giving clinical descriptions make the references useful to clinicians not in genetics. This now classic work is a central resource for anyone concerned in any way with genetic aspects of human disease.

• Copyright 2004 by the American College of Physicians