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Cryptosporidium Infection and CD4 Counts
- Timothy Flanigan, MD;
- Christopher Whalen, MD;
- John Turner, MD;
- Rosemary Soave, MD;
- Joseph Toerner, MD;
- Diane Havlir, MD; and
- Donald Kotler, MD
Excerpt
Cryptosporidium is a coccidian parasite that infects the gastrointestinal tract in humans and can cause severe enteritis and malabsorption. Cryptosporidiosis is selflimited in immunocompetent persons, whereas in persons with the acquired immunodeficiency syndrome (AIDS), Cryptospondium infection causes persistent enteritis that is usually lifelong and refractory to treatment (1). In our clinical practices, we observed men infected with the human immunodeficiency virus (HIV) who had self-limited diarrhea due to Cryptosporidium infection. To better define the laboratory and clinical characteristics associated with self-limited compared with persistent disease, we did a retrospective chart review of HIV-seropositive patients with Cryptosporidium infection. We hypothesized that
This 100-word excerpt has been provided in the absence of an abstract.
Acknowledgments
Acknowledgments: The authors thank Richard E. DuBois, MD, for his assistance and Maureen Lemieux for preparation of the manuscript.
Article and Author Information
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For current author affiliations and addresses, see end of text.
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Grant Support: By the National Institutes of Health grants AI-25879 and AI-01038.
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Requests for Reprints: Timothy P. Flanigan, MD, Department of Geographic Medicine, The Miriam Hospital, 164 Summit Avenue, Providence, RI 02906.
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Current Author Addresses: Dr. Flanigan, Department of Geographic Medicine, The Miriam Hospital, 164 Summit Avenue, Providence, RI 02906.
Dr. Whalen: University Hospitals, Cleveland, OH 44106.
Dr. Turner: Graduate Hospital, Philadelphia, PA 19146.
Dr. Soave: New York Hospital-Cornell Medical Center, New York, NY 10021.
Dr. Toerner: Whitman Walker Clinic, Washington, DC 20009.
Dr. Havlir: University of California at San Diego, UCSD Treatment Center, San Diego, CA 92103.
Dr. Kotler: St. Luke's-Roosevelt Medical Center, New York, NY 10025.
