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Allergic Bronchopulmonary Aspergillosis with Adenopathy
- Christina E. Hantsch, BS; and
- Tonny Tanus, MD
Excerpt
Allergic bronchopulmonary aspergillosis, first described by Hinson and associates (1) in 1952, is a hypersensitivity reaction to the fungus Aspergillus. In patients with an underlying respiratory disorder such as asthma, the condition progresses to a fibrotic end stage unless it is detected early and treated aggressively with corticosteroids (2). The condition has been recognized more frequently in recent years, and the diagnosis is based on a combination of clinical, immunologic, and radiologic criteria (3). Characteristics of the condition include peripheral blood eosinophilia, immunologic reactivity to Aspergillus antigen, increased serum immunoglobulin E levels, central bronchiectasis, and pulmonary infiltrates. No cases of
Article and Author Information
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From McGaw Medical Center of Northwestern University, Chicago; and Evanston Hospital, Evanston, Illinois. For current author addresses, see end of text.
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Requests for Reprints: Tonny Tanus, MD, P.O. Box 1567, Evanston, IL 60204.
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Current Author Addresses: Dr. Tanus: Department of Medicine, Evanston Hospital, 2650 Ridge Avenue, Evanston, IL 60201.
Ms. Hantsch: Department of Medical Education, Northwestern University, McGaw Medical Center, 303 Chicago Avenue, Chicago, IL 60611.
