The Toxicity of Anticancer Drugs

Excerpt

A general survey of the toxicity problem, including the prediction of toxicity in humans from animal studies and neoplasm induction as a toxicity, is followed by detailed reviews by drug class (for example, antimetabolites, Vinca alkaloids) of the biochemical basis of toxicity, clinical manifestations, and possibilities for prevention. The closing chapters cover immunologic effects and the toxicities of response modifiers. Heavily documented.