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Lyme Disease: Recommendations for Diagnosis and Treatment
- Daniel W. Rahn, MD; and
- Stephen E. Malawista, MD
Abstract
The incidence and the endemic range of Lyme disease in the United States have increased steadily since the disease was originally recognized in Lyme, Connecticut, in 1975. Because of the varied clinical manifestations of this illness and the use of unstandardized serologic testing methods, diagnosis is often uncertain and treatment outcomes are often difficult to evaluate. The antibiotic regimens that are commonly used in clinical practice have changed rapidly. They show much regional variation with little critical comparison of treatment results. The clinical diagnosis and the literature on the treatment of the various stages of Lyme disease are reviewed. The reported data are supplemented with recommendations based on IS years of clinical experience with this illness.
Article and Author Information
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From the Yale University School of Medicine, New Haven, Connecticut. For current author addresses, see end of text.
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Grant Support: By grants AR 40452 and AR 07107 from the National Institutes of Health.
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Requests for Reprints: Daniel W. Rahn, MD, Yale University School of Medicine, Section of Rheumatology, P.O. Box 3333, 333 Cedar Street, New Haven, CT 06510-8056.
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Current Author Addresses: Drs. Rahn and Malawista: Yale University School of Medicine, Section of Rheumatology, P.O. Box 3333, 333 Cedar Street, New Haven, CT 06510-8056.
- © 1991 American College of Physicians
