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Diabetic Nephropathy: Urinary Albumin or Total Protein?
- Edward A. Sasse, PhD;
- Basil T. Doumas, PhD; and
- Jacob Lemann, Jr., MD
Excerpt
To the Editor: Increased rates of albumin excretion into the urine at rest or after exercise exceeding about 3(μg/min or 45 mg/day are an early manifestation of diabetic nephropathy and may be a more sensitive indicator of the onset of diabetic nephropathy than the measurement of urinary total protein (1, 2). We evaluated whether measurement of urinary albumin, a more difficult and costly procedure, offers any advantage over the measurement of urinary total protein in following patients with established diabetic nephropathy.
We studied 11 patients with established type I diabetic nephropathy. These patients were entered in the Collaborative Study of
This 100-word excerpt has been provided in the absence of an abstract.
Article and Author Information
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Grant Support: Supported in part by grants RR0058 and DK39908 from the United States Public Health Service.
