Lupus Anticoagulant

  1. Alpha S. Yap, B Med Sci, MBBS;
  2. Elizabeth E. Powell, MBBS;
  3. Catherine E. Yelland, MBBS;
  4. Robin H. Mortimer, MBBS; and
  5. Donald A. Perry-Keene, MBBS
  1. Royal Brisbane Hospital
    Brisbane, Queensland

    Australia 4029

    Excerpt

    To the Editor: In their recent review, Rao and colleagues (1) reported one case of bilateral adrenal hemorrhage associated with the lupus anticoagulant (Patient 3). We describe three patients who had adrenal hemorrhage associated with the lupus anticoagulant or anticardiolipin antibodies, or both.

    In case 1, a 42-year-old man presented with progressive lethargy, malaise, and weight loss. He was hyperpigmented and hypotensive (blood pressure 80/60 mm Hg). Two months before, he had had acute pain in his left loin followed by rightsided back pain, for which no cause had been found. Serum sodium was 125 mmol/L; potassium, 6.6 mmol/L; creatinine,

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