High Amylase Levels in Neoplasm-Related Pleural Effusion

Excerpt

Amylase levels elevated in pleural effusions are found in three categories. First, the commonest category is pancreatitis with or without pseudocyst formation or a direct pancreatic-pleural fistula. Second, and uncommonly, is rupture of the esophagus, usually recognized by a distinct clinical picture. Third, malignant effusion may have elevated amylase levels (1-13). We report the case of a patient in whom extremely high amylase levels in pleural effusion contributed to diagnosis of a lung neoplasm. We also review 33 additional reports in the literature.

Case Report A 67-year-old previously healthy man was hospitalized because of left chest pain and increasing dyspnea

This 100-word excerpt has been provided in the absence of an abstract.

Acknowledgments

Acknowledgments: The authors thank Drs. Kunhardt and Clark for reviewing the pathologic specimens, and Dr. Baum for his assistance in managing the patient.

Article and Author Information

  • From the Veterans Administration Hospital, Jackson Memorial Hospital, and University of Miami School of Medicine, Miami, Florida. For current author addresses, see end of text.

  • Request for Reprints: Mordechai R. Kramer, MD, Pulmonary Division, Mount Sinai Medical Center, 4300 Alton Road, Miami Beach, FL 33140.

  • Current Author Addresses: Dr. Kramer: Pulmonary Division, Mount Sinai Medical Center, Miami Beach, FL 33140.

    Dr. Saldana: Pathology Department, Jackson Memorial Medical Center, Miami, FL 33136.

    Dr. Cepero: Department of Medicine, Jackson Memorial Medical Center, Miami, FL 33136.

    Dr. Pitchenik: Pulmonary Division, Veterans Administration Medical Center, Miami, FL 33125.

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