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Nodular Pneumonitis after Chemotherapy for Germ Cell Tumors
- Donald L. Trump, MD;
- Eric Bartel, BS; and
- Myron Pozniak, MD
Excerpt
Cisplatin-bleomycin-based combination chemotherapy is curative for patients with extensive metastatic germ cell cancer (1, 2). Optimal management of these patients requires repeated serologic and radiographic assessment to monitor regression of disease after chemotherapy. If masses are seen by radiography after chemotherapy and serum markers are normal, surgical removal of these masses is indicated. Surgery will either confirm the eradication of all malignancy by revealing only mature teratoma or necrosis and fibrosis in these masses or reveal residual cancer requiring additional therapy (1, 2). We have noted the appearance of new nodular pulmonary infiltrates by computed tomographic (CT) scan of the
This 100-word excerpt has been provided in the absence of an abstract.
Acknowledgments
Acknowledgments: The authors thank Jessica Hsyu and Kathy Edge for preparation of the manuscript.
Article and Author Information
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From the University of Wisconsin Clinical Cancer Center, the University of Wisconsin Medical School, and the William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin. For current author addresses, see end of text.
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Grant Support: Partial support by a grant from the American Cancer Society Assistantship Program and a grant from the Paul B. Cohen Memorial Fund.
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Requests for Reprints: Donald L. Trump, MD, Duke University Medical Center, Box 3398, Durham, NC 27710.
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Current Author Addresses: Dr. Trump: Duke University Medical Center, Box 3398, Durham, NC 27710.
Mr. Bartel: University of Wisconsin Medical School, Madison, WI 53705. Dr. Pozniak: Room E3/311, Clinical Science Center, 600 Highland Avenue, Madison, WI 53792.
