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Thrombotic Thrombocytopenic Purpura in Patients with the Acquired Immunodeficiency Syndrome (AIDS)-Related Complex
A Report of Two Cases
- Jagadamma M.G. Nair, MD;
- Rita Bellevue, MD;
- Maud Bertoni, MD; and
- Harvey Dosik, MD
Abstract
Immune thrombocytopenia has been reported with increased incidence in high-risk persons such as intravenous drug addicts and homosexual men who have serologic evidence of infection with human immunodeficiency virus (HIV). Thrombotic thrombocytopenic purpura, generally regarded as a rare disorder, has also been seen in association with exposure to HIV. Two patients had classical symptoms and laboratory findings of thrombotic thrombocytopenic purpura and the acquired immunodeficiency syndrome (AIDS)-related complex. Both patients belong to high-risk groups. They were treated with conventional therapy for thrombotic thrombocytopenic purpura and followed for 3 months. Their response to treatment was no different from that of other groups of patients with this syndrome. This article alerts physicians to the possible association of thrombotic thrombocytopenic purpura, AIDS, and AIDS-related complex.
Article and Author Information
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From the Interfaith Medical Center State University of New York Health Science Center and Wyckoff Heights Hospital, Brooklyn, New York. For current author addresses, see end of text.
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Requests for Reprints: Rita Bellevue, MD, Department of Medicine, Interfaith Medical Center, 555 Prospect Place, Brooklyn, NY 11238.
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Current Author Addresses: Dr. Nair: Department of Medicine, Interfaith Medical Center, 555 Prospect Place, Brooklyn, NY 11238.
Drs. Bellevue and Dosik: Department of Medicine, Interfaith Medical Center, 555 Prospect Place, Brooklyn, NY 11238; and Department of Medicine, State University of New York Health Science Center, 450 Clarkson Avenue, Brooklyn, NY 11203.
Dr. Bertoni: Department of Laboratories, Wyckoff Heights Hospital, 374 Stockholm Street, Brooklyn, NY 11237.
- © 1988 American College of Physicians
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