Progress in the Treatment of Cytomegalovirus Pneumonia

  1. Ian Frank, MD; and
  2. Harvey M. Friedman, MD
  1. University of Pennsylvania,
    Philadelphia, Pennsylvania

    Excerpt

    The importance of cytomegalovirus infection in the immunocompromised host is well documented. Cytomegalovirus is the commonest form of life-threatening opportunistic viral infection in patients with the acquired immunodeficiency syndrome (AIDS) (1). The incidence of infection after renal transplantation, determined by rise in antibody titer or virus isolation, is 71%, averaged over 15 studies (2). Approximately 30% of heart transplant patients develop clinical cytomegalovirus disease, although subclinical infection can be documented in almost all patients (3). Cytomegalovirus is the commonest infectious cause of death after allogeneic bone marrow transplantation, primarily because of cytomegalovirus pneumonia (4).

    The clinical characteristics of cytomegalovirus pneumonia

    This 100-word excerpt has been provided in the absence of an abstract.

    Article and Author Information

    • Grant Support: Partial support by National Institutes of Health grant HD18957.

    • Requests for Reprints: Harvey Friedman, MD, 534 Johnson Pavilion/ 6073, University of Pennsylvania, Philadelphia, PA 19104.

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    1. Ann Intern Med November 15, 1988 vol. 109 no. 10 769-771
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