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Pseudothromboembolism in Myeloid Metaplasia
- JAMES J. GORDON, M.D.;
- MILTON AUSTIN, M.D.; and
- E. STEPHEN KURTIDES, M.D.
Excerpt
A patient with postpolycythemic myeloid metaplasia had recurrent pulmonary emboli despite adequate heparin therapy. At postmortem examination, the pulmonary thromboemboli were shown to be clusters of hematopoietic tissue, obstructing multiple branches of the pulmonary arterial tree. To our knowledge, this complication of myeloid metaplasia has not been reported previously.
A 73-year-old white man with a history of polycythemia vera and severe aortic stenosis was admitted in February 1986 for aortic valve replacement. His polycythemia vera had been diagnosed at age 33 and managed with phlebotomy alone for 31 years. In 1983 he developed malaise, anorexia, and weight loss, secondary to
Acknowledgments
ACKNOWLEDGMENTS: The authors thank Drs. Joseph Golbus, Joel R. Bernstein, and Hartmann H. R. Friederici for editorial and technical assistance.
Article and Author Information
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▸Requests for reprints should be addressed to E. Stephen Kurtides, M.D.; Department of Medicine, Evanston Hospital, 2650 Ridge Avenue; Evanston, IL 60201.
