Spastic Paraparesis and Dual Exposure to Human T-Lymphotropic Virus Type I and Human T-Lymphotropic Virus Type IV

  1. J. HUGON, M.D.;
  2. M. DUMAS, M.D.;
  3. J. M. VALLAT, M.D.;
  4. F. DENIS, M.D.;
  5. M. PlQUEMAL, M.D.;
  6. C. GIORDANO, M.D.; and
  7. F. BARIN, M.D.
  1. Centre Hospitalier Regional et Universitaire;
    Limoges,
    France
  2. Centre Hospitalier Regional et Universitaire;
    Abidjan, Ivory Coast,
    Africa
  3. Centre Hospitalier Regional et Universitaire;
    Tours,
    France

    Excerpt

    To the editor: Infection with human T-lymphotropic virus type I (HTLV-I) has been associated with adult T-cell leukemia-lymphoma and, more recently, with tropical spastic paraparesis (1). A new retrovirus (HTLV-IV) similar to that known as simian T-lymphotropic virus type III has been isolated in apparently healthy people in Senegal (2). We report the case of a West-African patient with progressive spastic paraplegia and dual exposure to HTLV-I and HTLV-IV.

    A 32-year-old black man born in the western part of Ivory Coast and living in Abidjan had a neurologic examination in June 1985 to determine the cause of progressive difficulty in

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