Risk for the Acquired Immunodeficiency Syndrome Among Thrombocytopenic and Nonthrombocytopenic Homosexual Men Seropositive for the Human Immunodeficiency Virus

  1. ROBERT S. HOLZMAN, M.D.;
  2. CHRISTINA M. WALSH, M.D.; and
  3. SIMON KARPATKIN, M.D.
  1. New York, New York

    Abstract

    A group of 44 homosexual patients with immune thrombocytopenia and serologic evidence of infection with the human immunodeficiency virus (HIV) was observed for a total of 844 person-months. The risk for the acquired immunodeficiency syndrome (AIDS), an actuarial incidence of 36.5% in 37 months, was no different than that reported for seropositive homosexual men from New York who are nonthrombocytopenic and asymptomatic. A statistical analysis comparing the hazard function with a constant-risk model showed that the hazard of developing AIDS was not constant but increased with duration of seropositivity.

    Article and Author Information

    • ▸From the New York University School of Medicine; New York, New York.

    • Grant support: in part by grant HL-13336-16 from the National Heart, Lung and Blood Institute, and grant C-000534 from the New York State Department of Health's Acquired Immune Deficiency Syndrome Institute.

    • ▸Requests for reprints should be addressed to Simon Karpatkin, M.D.; New York University School of Medicine, Department of Medicine, 550 First Avenue, New York, NY 10016.

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