Multiple Squamous Cell Carcinomas and Human Immunodeficiency Virus Infection

  1. WYLIE L. OVERLY, M.D.; and
  2. DONALD J. JAKUBEK, M.D.
  1. Latrobe Area Hospital;
    Labrobe, PA 15650

    Excerpt

    To the editor: Adenosquamous cell carcinomas of the lung (1), squamous cell carcinomas of the epiglottis (2), and squamous cell carcinomas of the oral cavity (3) have been described in patients with impaired cellular immunity associated with the acquired immunodeficiency syndrome or with infection by the human immunodeficiency virus (HIV). We report multiple squamous cell carcinomas of the skin in an elderly man that occurred after he developed antibodies to HIV.

    In September 1984, a 79-year-old white man with lifelong factor IX deficiency had a positive serologic test for HIV. Other findings included an OKT4:OKT8 (helper:suppressor) ratio of 0.07, oral

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