Transmission of Human Immunodeficiency Virus by Transplantation of a Renal Allograft, with Development of the Acquired Immunodeficiency Syndrome
- PREM KUMAR, M.D.;
- JAMES E. PEARSON, M.S.;
- DAVID H. MARTIN, M.D.;
- STEPHEN H. LEECH, M.D., Ph.D.;
- PAUL D. BUISSERET, M.D.;
- HELEN C. BEZBAK, M.D.;
- FRANCISCO M. GONZALEZ, M.D.;
- JOHN R. ROYER, M.D.;
- H. Z. STREICHER, M.D.; and
- W. CARL SAXINGER, Ph.D.
- Louisiana State University Medical Center New Orleans, Louisiana; Highland Medical Group Los Angeles, California ; and National Cancer Institute Bethesda, Maryland
Excerpt
Human immunodeficiency virus (HIV) can be transmitted by seminal fluid and the transfusion of blood and blood products. This case report shows that organ donors may be a source for HIV infection.
Recipient: A 38-year-old woman received a renal transplant in 1982 from her HLA-identical brother. Antirejection therapy consisted of prednisone and azathioprine. During the first hospitalization, she developed fever, for which no explanation was found.
Subsequently, she had three additional prolonged hospitalizations for the evaluation of fever. On the first of these, 6 weeks after transplantation, her total leukocyte count was 2700/mm3 with 70% polymorphonuclear cells, 5% band forms,
Article and Author Information
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▸ Requests for reprints should be addressed to Prem Kumar, M.D.; Department of Medicine, LSU Medical Center, 1542 Tulane Avenue; New Orleans, LA 70112.
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