Possible Female-to-Female Transmission of Human Immunodeficiency Virus

  1. MICHAEL MARMOR, Ph.D.;
  2. LEE R. WEISS, M.D.;
  3. MARGARET LYDEN, R.N., M.P.H.;
  4. STANLEY H. WEISS, M.D.;
  5. W. CARL SAXINGER, Ph.D.;
  6. THOMAS J. SPIRA, M.D.; and
  7. PAUL M. FEORINO, Ph.D.
  1. New York University Medical Center;
    New York, NY 10010-2598
  2. National Cancer Institute;
    Bethesda, MD 20892
  3. Centers for Disease Control;
    Atlanta, GA 30333

    Excerpt

    To the editor: A case of the acquired immunodeficiency syndrome (AIDS) in a lesbian without any recognized risk factors was reported in 1984 (1). Consistent with that observation, we report the apparent female-to-female sexual transmission of human immunodeficiency virus (HIV).

    Patient 1, a 25-year-old white woman and a parenteral drug abuser, presented in November 1981 with unexplained weight loss. She had cervical lymphadenopathy and subsequently became chronically ill and developed anergy to skin-test antigens. In July 1984 a biopsy sample of the left axillary lymph node disclosed Kaposi's sarcoma, and antibodies to HIV were found by enzyme-linked immunosorbent assay and

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