Meme Machines

  1. GEORGE A. DIAMOND, M.D.
  1. Division of Cardiology, Cedars-Sinai Medical Center, and the UCLA School of Medicine,
    Los Angeles, California

    Excerpt

    The same man who so succinctly digested the wisdom of multivariate analysis more than 2000 years before Thomas Bayes, Karl Friedrich Gauss, and Sir Ronald Fisher also served up a good deal of the "predigested" (2) variety in the form of his aphorisms (3). It is unlikely that you will encounter any of the 412 surviving Hippocratic aphorisms on morning rounds, but although most of them are hopelessly dated in content, they remain timeless in style. The clinical "pearl," the rule-of-thumb, the mnemonic, the algorithm, the heuristic, and the decision tree all trace their evolutionary lineage back to these aphorisms.

    This 100-word excerpt has been provided in the absence of an abstract.

    Acknowledgments

    ACKNOWLEDGMENTS: Grant support: in part by Specialized Center of Research (SCOR) grant HL-17651 from the National Institutes of Health.

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