Persistent Infection with Human T-Lymphotropic Virus Type III/Lymphadenopathy-Associated Virus in Apparently Healthy Homosexual Men

  1. HAROLD W. JAFFE, M.D.;
  2. PAUL M. FEORINO, Ph.D.;
  3. WILLIAM W. DARROW, Ph.D.;
  4. PAUL M. O'MALLEY, B.A.;
  5. JANE P. GETCHELL, Dr.P.H.;
  6. DONNA T. WARFIELD, B.S.;
  7. BONNIE M. JONES, B.S.;
  8. DEAN F. ECHENBERG, M.D., Ph.D.;
  9. DONALD P. FRANCIS, M.D.; and
  10. JAMES W. CURRAN, M.D.
  1. Centers for Disease Control,
    Atlanta, Georgia
    ; and Department of Public Health,
    San Francisco, California.

    Excerpt

    The acquired immunodeficiency syndrome appears to be caused by a retrovirus called both lymphadenopathy-associated virus (LAV) and human T-lymphotropic virus type III (HTLV-III) (1, 2). Several surveys have shown serologic evidence of infection with this virus in healthy persons from groups at increased risk for the acquired immunodeficiency syndrome (3). Because relatively little is known about the natural history of infection with this virus in such persons, we studied a group of apparently healthy homosexual men with serologic evidence of HTLV-III/LAV infection to determine the duration of their seropositivity, their immunologic status, and the frequency of isolation of HTLV-III/LAV from

    This 100-word excerpt has been provided in the absence of an abstract.

    Acknowledgments

    ACKNOWLEDGMENTS: The authors thank Lynn Barashick and Barbara Kilbourne for assistance with specimen handling; and J. Steven McDougal, M.D., for immunologic testing.

    Article and Author Information

    • ▸Requests for reprints should be addressed to Harold W. Jaffe, M.D.; AIDS Activity, Centers for Disease Control; Atlanta, GA 30333.

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