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Hypercalcemia and Disseminated Cytomegalovirus Infection in the Acquired Immunodeficiency Syndrome
Abstract
Two patients with the acquired immunodeficiency syndrome and disseminated cytomegalovirus infection developed hypercalcemia associated with suppressed parathyroid gland activity. Neither patient had evidence of a malignant, endocrinologic, granulomatous, or drug-related cause for hypercalcemia. Increased osteoclastic bone resorption induced by cytomegalovirus or human T-lymphotropic virus III infection may have been the cause for the hypercalcemia. Physicians should be alert for the occurrence of endocrinologic and metabolic problems in immunosuppressed patients.
Article and Author Information
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▸From the Departments of Critical Care Medicine and Internal Medicine, Endocrinology and Metabolism, Bethesda Naval Hospital, and the Department of Medicine, Uniformed Services University of the Health Sciences; Bethesda, Maryland.
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A report on the disseminated Histoplasma capsulatum infection associated with the acquired immunodeficiency syndrome in this patient was presented as an abstract by Drs Bauman and Romeo at the Air Force Regional Meeting of the American College of Physicians, Colorado Springs, Colorado, 26 March 1984.
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The opinions expressed herein are those of the authors and are not to be construed as reflecting the views of the Navy Department, of the Naval Service at large, or of the Department of Defense.
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▸Requests for reprints should be addressed to Bart Chernow, M.D.; Critical Care Medicine, Box #123, Naval Hospital; Bethesda, MD 20814.
- © 1985 American College of Physicians
